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Literature summary extracted from

  • Flowers, M.T.; Ntambi, J.M.
    Stearoyl-CoA desaturase and its relation to high-carbohydrate diets and obesity (2009), Biochim. Biophys. Acta, 1791, 85-91.
    View publication on PubMedView publication on EuropePMC

Organism

EC Number Organism UniProt Comment Textmining
1.14.19.1 Mus musculus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.14.19.1 adipose tissue
-
 Mus musculus
-
1.14.19.1 liver
-
 Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.19.1 palmitoyl-CoA + NADH + H+ + O2
-
 Mus musculus palmitoleoyl-CoA + NAD+ + H2O
-
 ?
1.14.19.1 stearoyl-CoA + NADH + H+ + O2
-
 Mus musculus oleoyl-CoA + NAD+ + H2O
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.14.19.1 SCD1
-
 Mus musculus
1.14.19.1 stearoyl-CoA desaturase
-
 Mus musculus
1.14.19.1 stearoyl-coenzyme A desaturase-1
-
 Mus musculus

Cofactor

EC Number Cofactor Comment Organism Structure
1.14.19.1 NADH
-
 Mus musculus

Expression

EC Number Organism Comment Expression
1.14.19.1 Mus musculus intracerebroventricular glucose administration strongly decreases hepatic Scd1 down
1.14.19.1 Mus musculus dietary saturated fat strongly induces Scd1 expression up

General Information

EC Number General Information Comment Organism
1.14.19.1 physiological function mice lacking Scd1 are protected from obesity and insulin resistance and are characterized by decreased fatty acid synthesis and increased fatty acid oxidation Mus musculus