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Literature summary extracted from

  • Macdonald, M.L.; Bissada, N.; Vallance, B.A.; Hayden, M.R.
    Absence of stearoyl-CoA desaturase-1 does not promote DSS-induced acute colitis (2009), Biochim. Biophys. Acta, 1791, 1166-1172.
    View publication on PubMedView publication on EuropePMC

Organism

EC Number Organism UniProt Comment Textmining
1.14.19.1 Mus musculus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.19.1 stearoyl-CoA + NADH + H+ + O2
-
 Mus musculus oleoyl-CoA + NAD+ + H2O
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.14.19.1 SCD1
-
 Mus musculus
1.14.19.1 stearoyl-CoA desaturase-1
-
 Mus musculus

Cofactor

EC Number Cofactor Comment Organism Structure
1.14.19.1 NADH
-
 Mus musculus

General Information

EC Number General Information Comment Organism
1.14.19.1 physiological function absence of stearoyl-CoA desaturase-1 leads to chronic inflammation of the skin and increased susceptibility to atherosclerosis, while also increasing plasma inflammatory markers, but does not promote dextran sulfate sodium-induced acute colitis Mus musculus