Literature summary extracted from

Cox, A.G.; Peskin, A.V.; Paton, L.N.; Winterbourn, C.C.; Hampton, M.B.
Redox potential and peroxide reactivity of human peroxiredoxin 3 (2009), Biochemistry, 48, 6495-6501.

Localization

EC Number	Localization	Comment	Organism	GeneOntology No.	Textmining
1.11.1.24	mitochondrion	localized to the mitochondrial matrix	Homo sapiens	5739	-

Organism

EC Number	Organism	UniProt	Comment	Textmining
1.11.1.24	Homo sapiens	-	-	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
1.11.1.24	H2O2 + reduced thioredoxin	Prx 3 displays strong reactivity with H2O2	Homo sapiens	H2O + oxidized thioredoxin	-	?
1.11.1.24	iodoacetamide + reduced thioredoxin	Prx 3 reacts very slowly with iodoacetamide	Homo sapiens	?	-	?
1.11.1.24	N-ethylmaleimide + reduced thioredoxin	Prx 3 reacts very slowly with N-ethylmaleimide	Homo sapiens	?	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
1.11.1.24	peroxiredoxin 3	a typical 2-Cys peroxiredoxin	Homo sapiens
1.11.1.24	Prx 3	-	Homo sapiens

Cofactor

EC Number	Cofactor	Comment	Organism	Structure
1.11.1.24	thioredoxin	-	Homo sapiens

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Release 2023.1 (January 2023)