Any feedback?
Literature summary extracted from
- Function of Glu-469 in the acid-base catalysis of thioredoxin reductase from Drosophila melanogaster (2008), Biochemistry, 47, 12769-12776.
Protein Variants
| EC Number | Protein Variants | Comment | Organism |
|---|---|---|---|
| 1.8.1.9 | E469A | the mutant retains 28% of the wild type activity | Drosophila melanogaster |
| 1.8.1.9 | E469Q | the mutant retains 35% of the wild type activity | Drosophila melanogaster |
| 1.8.1.9 | E470A | the mutant retains 70% of the wild type activity | Drosophila melanogaster |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.8.1.9 | Drosophila melanogaster | - |
- |
- |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.8.1.9 | thioredoxin disulfide + NADPH + H+ | - |
Drosophila melanogaster | thioredoxin + NADP+ | - |
r |  |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 1.8.1.9 | EC 1.6.4.5 | formerly | Drosophila melanogaster |
| 1.8.1.9 | thioredoxin reductase | - |
Drosophila melanogaster |
| 1.8.1.9 | TrxR | - |
Drosophila melanogaster |
Cofactor
| EC Number | Cofactor | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.8.1.9 | FAD | - |
Drosophila melanogaster | |
| 1.8.1.9 | NADPH | - |
Drosophila melanogaster | |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
