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Literature summary extracted from

  • Zhao, Z.; Rothery, R.A.; Weiner, J.H.
    Transient kinetic studies of heme reduction in Escherichia coli nitrate reductase A (NarGHI) by menaquinol (2003), Biochemistry, 42, 5403-5413.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.7.5.1 2-n-heptyl-4-hydroxyquinoline N-oxide quinol-binding-site inhibitor, elicits a much stronger inhibitory effect than stigmatellin on the reoxidation of the hemes Escherichia coli
1.7.5.1 Stigmatellin quinol-binding-site inhibitor Escherichia coli

Organism

EC Number Organism UniProt Comment Textmining
1.7.5.1 Escherichia coli
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.7.5.1 nitrate + 2-methyl-1,4-naphthoquinol i.e. menadiol Escherichia coli nitrite + 2-methyl-1,4-naphthoquinone + H2O
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.7.5.1 NarGHI
-
 Escherichia coli
1.7.5.1 nitrate reductase A
-
 Escherichia coli

Cofactor

EC Number Cofactor Comment Organism Structure
1.7.5.1 heme the reduction of NarGHI hemes by menaquinol, the reduction exhibits four phases, a transient species associated with the enzyme is kinetically correlated to the second reduction of the hemes Escherichia coli
1.7.5.1 menaquinone there are more than one menaquinol binding sites in NarGHI Escherichia coli