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Literature summary extracted from
- Variably modulated gating of the 26S proteasome by ATP and polyubiquitin (2009), Biochem. J., 421, 397-404.
Activating Compound
| EC Number | Activating Compound | Comment | Organism | Structure |
|---|---|---|---|---|
| 5.6.1.5 | additional information | Rip-1 does not alter ATPase activity | Bos taurus | |
| 5.6.1.5 | polyubiquitin | modest but reproducible stimulatory effect on 26S proteasome ATPase activity | Bos taurus |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 5.6.1.5 | ATPgammaS | inhibits 26S proteasome ATPase activity over the same concentration range in which it stimulates peptidase activity | Bos taurus |  |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 5.6.1.5 | Bos taurus | - |
- |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 5.6.1.5 | erythrocyte | - |
Bos taurus | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 5.6.1.5 | ATP + H2O + polypeptide | - |
Bos taurus | ADP + phosphate + unfolded polypeptide | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 5.6.1.5 | 26S proteasome | - |
Bos taurus |
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Release 2023.1 (January 2023)
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