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Literature summary extracted from

  • Munoz-Clares, R.A.; Diaz-Sanchez, A.G.; Gonzalez-Segura, L.; Montiel, C.
    Kinetic and structural features of betaine aldehyde dehydrogenases: Mechanistic and regulatory implications (2010), Arch. Biochem. Biophys., 493, 71-81.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.2.1.8 NAD+ substrate inhibition by high concentrations of NAD+ Pseudomonas aeruginosa

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
1.2.1.8 K+
-
 Pseudomonas aeruginosa

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.2.1.8 betaine aldehyde + NAD(P)+ + H2O Pseudomonas aeruginosa
-
 glycine betaine + NAD(P)H + H+
-
 ir

Organism

EC Number Organism UniProt Comment Textmining
1.2.1.8 Pseudomonas aeruginosa Q9HTJ1
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.2.1.8 3-aminopropionaldehyde + NAD(P)+ + H2O
-
 Pseudomonas aeruginosa ?
-
 ?
1.2.1.8 3-dimethylsulfoniopropionaldehyde + NAD(P)+ + H2O
-
 Pseudomonas aeruginosa ?
-
 ?
1.2.1.8 4-N-trimethylaminobutyraldehyde + NAD(P)+ + H2O
-
 Pseudomonas aeruginosa ?
-
 ?
1.2.1.8 betaine aldehyde + NAD(P)+ + H2O
-
 Pseudomonas aeruginosa glycine betaine + NAD(P)H + H+
-
 ir
1.2.1.8 gamma-aminobutyraldehyde + NAD(P)+ + H2O
-
 Pseudomonas aeruginosa ?
-
 ?
1.2.1.8 additional information BADH can also use as substrates aminoaldehydes and other quaternary ammonium and tertiary sulfonium compounds, thereby participating in polyamine catabolism and in the synthesis of gamma-aminobutyrate, carnitine, and 3-dimethylsulfoniopropionate Pseudomonas aeruginosa ?
-
 ?

Subunits

EC Number Subunits Comment Organism
1.2.1.8 homodimer
-
 Pseudomonas aeruginosa

Synonyms

EC Number Synonyms Comment Organism
1.2.1.8 BADH
-
 Pseudomonas aeruginosa
1.2.1.8 betaine aldehyde dehydrogenase
-
 Pseudomonas aeruginosa
1.2.1.8 betaine aldehyde:NAD(P)+ oxidoreductase
-
 Pseudomonas aeruginosa
1.2.1.8 PaBADH
-
 Pseudomonas aeruginosa

Cofactor

EC Number Cofactor Comment Organism Structure
1.2.1.8 NAD+
-
 Pseudomonas aeruginosa
1.2.1.8 NADP+
-
 Pseudomonas aeruginosa