Literature summary extracted from

Wagner, A.E.; Hug, H.; Goessl, R.; Riss, G.; Mussler, B.; Elste, V.; Rimbach, G.; Barella, L.
The natural compound ascorbigen modulates NADPH-quinone oxidoreductase (NQO1) mRNA and enzyme activity levels in cultured liver cells and in laboratory rats (2008), Ann. Nutr. Metab., 53, 122-128.

Organism

EC Number	Organism	UniProt	Comment	Textmining
1.6.5.10	Rattus norvegicus	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
1.6.5.10	liver	NQO1 activity is elevated (up to 20%) by ascorbigen treatment	Rattus norvegicus	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
1.6.5.10	menadione + NADPH + H+	-	Rattus norvegicus	menadiol + NADP+	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
1.6.5.10	NADPH-quinone oxidoreductase	-	Rattus norvegicus
1.6.5.10	NQO1	-	Rattus norvegicus

Cofactor

EC Number	Cofactor	Comment	Organism	Structure
1.6.5.10	NADPH	-	Rattus norvegicus

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Release 2023.1 (January 2023)