Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Uramatsu, S.; Liu, G.; Yang, Q.; Uramatsu, M.; Chi, H.; Lu, J.; Yamashita, K.; Kodama, H.
    Characterization of prolidase I and II purified from normal human erythrocytes: comparison with prolidase in erythrocytes from a patient with prolidase deficiency (2009), Amino Acids, 37, 543-551.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.4.13.9 D,L-ethionine enhances the activity of isozyme prolidase I, D,L-ethionine strongly enhances the activity of isozyme prolidase II compared with L-ethionine Homo sapiens
3.4.13.9 D,L-homocysteine enhances the activity of isozyme prolidase I at low concentration Homo sapiens
3.4.13.9 D,L-homocysteine weakly enhances the activity of isozyme prolidase II Homo sapiens
3.4.13.9 D,L-methionine slightly enhances the activity of isozyme prolidase I at low concentration Homo sapiens
3.4.13.9 D,L-methionine the activity of isozyme prolidase II against L-Met-L-Pro is enhanced by D,L-methionine Homo sapiens
3.4.13.9 D-ethionine enhances the activity of isozymes prolidase I and II Homo sapiens
3.4.13.9 D-methionine the activity of isozyme prolidase I against Gly-L-Pro is strongly enhanced by D-methionine Homo sapiens
3.4.13.9 D-methionine the activity of isozyme prolidase II against L-Met-L-Pro is enhanced by D-methionine Homo sapiens
3.4.13.9 L-ethionine enhances the activity of isozyme prolidase I Homo sapiens
3.4.13.9 L-methionine slightly enhances the activity of isozyme prolidase I at low concentration Homo sapiens
3.4.13.9 L-methionine the activity of isozyme prolidase II against L-Met-L-Pro is enhanced by L-methionine Homo sapiens
3.4.13.9 additional information N-acetyl-L-methionine has no effect on activity of isozymes prolidase I and prolidase II Homo sapiens

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.13.9 D,L-homocysteine inhibits the activity at 50 mM Homo sapiens
3.4.13.9 D,L-homocysteine-thiolactone inhibits the activities of isozymes prolidase I and II in a concentration-dependent manner Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
3.4.13.9 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.13.9 erythrocyte
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.13.9 Gly-L-Pro + H2O
-
 Homo sapiens Gly + L-Pro
-
 ?
3.4.13.9 L-Met-L-Pro + H2O
-
 Homo sapiens L-Met + L-Pro
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.4.13.9 prolidase I isozyme Homo sapiens
3.4.13.9 prolidase II isozyme Homo sapiens