Literature summary extracted from

Czegle, I.; Margittai, E.; Senesi, S.; Benedetti, A.; Banhegyi, G.
Different expression and distribution of 11beta-hydroxysteroid dehydrogenase type 1 in obese and lean animal models of type 2 diabetes (2008), Acta Physiol. Hung., 95, 419-424.

Localization

EC Number	Localization	Comment	Organism	GeneOntology No.	Textmining
1.1.1.146	microsome	-	Rattus norvegicus	-	-

Molecular Weight [Da]

EC Number	Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
1.1.1.146	32000	-	SDS-PAGE	Rattus norvegicus

Organism

EC Number	Organism	UniProt	Comment	Textmining
1.1.1.146	Rattus norvegicus	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
1.1.1.146	adipose tissue	the activity of 11beta-HSD1 is increased in adipose tissue of obese Zucker rats	Rattus norvegicus	-
1.1.1.146	liver	the activity of 11beta-HSD1 is decreased in the liver of obese Zucker rats	Rattus norvegicus	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
1.1.1.146	cortisol + NADP+	-	Rattus norvegicus	cortisone + NADPH	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
1.1.1.146	11beta-HSD1	-	Rattus norvegicus
1.1.1.146	11beta-hydroxysteroid dehydrogenase type 1	-	Rattus norvegicus

Cofactor

EC Number	Cofactor	Comment	Organism	Structure
1.1.1.146	NADPH	dependent on	Rattus norvegicus

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Release 2023.1 (January 2023)