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Literature summary extracted from

  • Chen, R.J.; Chung, T.Y.; Li, F.Y.; Lin, N.H.; Tzen, J.T.
    Effect of sugar positions in ginsenosides and their inhibitory potency on Na+/K+-ATPase activity (2009), Acta Pharmacol. Sin., 30, 61-69.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
7.2.2.13 12,20-dihydroxydammar-24-en-3-yl 2-O-D-glucopyranosyl-D-glucopyranoside
-
 Sus scrofa
7.2.2.13 12,20-dihydroxydammar-24-en-3-yl D-glucopyranoside
-
 Sus scrofa
7.2.2.13 3-[(2-O-D-glucopyranosyl-D-glucopyranosyl)oxy]-12-hydroxydammar-24-en-20-yl D-glucopyranoside
-
 Sus scrofa
7.2.2.13 dammar-24-ene-3,12,20-triol
-
 Sus scrofa
7.2.2.13 dammar-24-ene-3,6,12,20-tetrol
-
 Sus scrofa
7.2.2.13 oleanolic acid
-
 Sus scrofa
7.2.2.13 Ouabain
-
 Sus scrofa

Organism

EC Number Organism UniProt Comment Textmining
7.2.2.13 Sus scrofa
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
7.2.2.13 cerebral cortex
-
 Sus scrofa
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
7.2.2.13 ATP + H2O + Na+/in + K+/out
-
 Sus scrofa ADP + phosphate + Na+/out + K+/in
-
 ?

Synonyms

EC Number Synonyms Comment Organism
7.2.2.13 Na+/K+-ATPase
-
 Sus scrofa

IC50 Value

EC Number IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
7.2.2.13 0.00045
-
-
 Sus scrofa Ouabain
7.2.2.13 0.055
-
-
 Sus scrofa 12,20-dihydroxydammar-24-en-3-yl D-glucopyranoside