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Literature summary extracted from

  • Yan, H.; He, P.; Cheng, H.R.; Shen, A.; Jiang, N.
    Cloning, sequencing and characterization of the alpha-aminoadipate reductase gene (LYS2) from Saccharomycopsis fibuligera (2007), Yeast, 24, 189-199.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
1.2.1.95 additional information growth on medium containing lysine as the sole nitrogen source Saccharomycopsis fibuligera

Application

EC Number Application Comment Organism
1.2.1.95 additional information the sequence of the Saccharomycopsis fibuligera alpha-aminoadipate reductase gene Lys2p has the highest identity of 53% with the AAR of Candida albicans SC5314 and an identity of 51% with that of Saccharomyces cerevisiae. Expression of the ORF of SfLYS2 in a lys2- strain of Saccharomyces cerevisiae can functionally complement the lysine mutant of the Saccharomyces cerevisiae strain. Cloning of SfLYS2 may provide a general tool in developing genetics-based studies not only with Saccharomycopsis fibuligera but also with Saccharomyces cerevisiae Saccharomycopsis fibuligera

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.2.1.95 expression of the ORF of the Saccharomycopsis fibuligera alpha-aminoadipate reductase gene (LYS2) in a lys2- strain of Saccharomyces cerevisiae Saccharomycopsis fibuligera

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.2.1.95 alpha-aminoadipate inhibitory effect can be reversed by adding methionine Saccharomycopsis fibuligera

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining

Organism

EC Number Organism UniProt Comment Textmining
1.2.1.95 Saccharomycopsis fibuligera Q1W284
-
-
1.2.1.95 Saccharomycopsis fibuligera PD70 Q1W284
-
-

Synonyms

EC Number Synonyms Comment Organism
1.2.1.95 AAR
-
 Saccharomycopsis fibuligera
1.2.1.95 alpha-aminoadipate reductase
-
 Saccharomycopsis fibuligera