Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Souza, A.D.; Rodrigues-Filho, E.; Souza, A.Q.; Pereira, J.O.; Calgarotto, A.K.; Maso, V.; Marangoni, S.; Da Silva, S.L.
    Koninginins, phospholipase A2 inhibitors from endophytic fungus Trichoderma koningii (2008), Toxicon, 51, 240-250.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.1.4 koninginin E KonE, isolated from Trichoderma koningii, inhibits edema-inducing, myotoxic and enzymatic activities of PLA2. Action mode in comparison to vitmain E inhibition Bothrops jararacussu
3.1.1.4 koninginin E KonE, isolated from Trichoderma koningii, inhibits edema-inducing, myotoxic and enzymatic activities of PLA2 Homo sapiens
3.1.1.4 koninginin F KonF, isolated from Trichoderma koningii, inhibits edema-inducing, myotoxic and enzymatic activities of PLA2. Action mode in comparison to vitmain E inhibition Bothrops jararacussu
3.1.1.4 koninginin F KonF, isolated from Trichoderma koningii, inhibits edema-inducing, myotoxic and enzymatic activities of PLA2 Homo sapiens
3.1.1.4 additional information no inhibition by koninginin A, KonA, isolated from Trichoderma koningii Bothrops jararacussu
3.1.1.4 additional information no inhibition by koninginin A, KonA, isolated from Trichoderma koningii Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.1.1.4 extracellular
-
 Bothrops jararacussu
-
-
3.1.1.4 extracellular the group IIA enzyme is secreted Homo sapiens
-
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.1.1.4 Ca2+
-
 Homo sapiens
3.1.1.4 Ca2+
-
 Bothrops jararacussu

Organism

EC Number Organism UniProt Comment Textmining
3.1.1.4 Bothrops jararacussu
-
-
-
3.1.1.4 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.1.4 venom
-
 Bothrops jararacussu
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.1.4 1-hexadecanoyl-2-(10-(1-pyrene)decanoyl)-sn-glycero-3-phosphoglycerol + H2O
-
 Homo sapiens 1-hexadecanoyl-sn-glycero-3-phosphoglycerol + 10-(1-pyrene)decanoic acid
-
 ?
3.1.1.4 1-hexadecanoyl-2-(10-(1-pyrene)decanoyl)-sn-glycero-3-phosphoglycerol + H2O
-
 Bothrops jararacussu 1-hexadecanoyl-sn-glycero-3-phosphoglycerol + 10-(1-pyrene)decanoic acid
-
 ?
3.1.1.4 4-nitro-3-octanoyloxy-benzoic acid + H2O
-
 Homo sapiens ?
-
 ?
3.1.1.4 4-nitro-3-octanoyloxy-benzoic acid + H2O
-
 Bothrops jararacussu ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.1.1.4 More a group IIB isozyme Bothrops jararacussu
3.1.1.4 PLA2
-
 Bothrops jararacussu
3.1.1.4 PLA2 a group IIA isozyme Homo sapiens

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
3.1.1.4 37
-
 assay at Homo sapiens
3.1.1.4 37
-
 assay at Bothrops jararacussu

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.1.1.4 8
-
 assay at Homo sapiens
3.1.1.4 8
-
 assay at Bothrops jararacussu