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Literature summary extracted from

  • Bitto, E.; Huang, Y.; Bingman, C.A.; Singh, S.; Thorson, J.S.; Phillips, G.N. Jr.
    The structure of flavin-dependent tryptophan 7-halogenase RebH (2008), Proteins, 70, 289-293.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.14.19.9 expression in Escherichia coli Lentzea aerocolonigenes

Crystallization (Commentary)

EC Number Crystallization (Comment) Organism
1.14.19.9 hanging drop method, structural analysis of RebH in its apo-form as well as in a complex with both tryptophan and FAD Lentzea aerocolonigenes

Organism

EC Number Organism UniProt Comment Textmining
1.14.19.9 Lentzea aerocolonigenes Q8KHZ8
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.14.19.9 recombinant enzyme Lentzea aerocolonigenes

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.19.9 L-tryptophan + FADH2 + Br- + O2 + H+
-
 Lentzea aerocolonigenes 7-bromo-L-tryptophan + FAD + H2O
-
 ?
1.14.19.9 L-tryptophan + FADH2 + Cl- + O2 + H+
-
 Lentzea aerocolonigenes 7-chloro-L-tryptophan + FAD + H2O
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.14.19.9 RebH
-
 Lentzea aerocolonigenes

Cofactor

EC Number Cofactor Comment Organism Structure
1.14.19.9 FADH2
-
 Lentzea aerocolonigenes