EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
5.3.99.3 | additional information | mPGES-1 expression is upregulated in COX-1 and COX-2 knock-out cells | Mus musculus |
EC Number | Application | Comment | Organism |
---|---|---|---|
5.3.99.3 | medicine | mPGES-1 could be a potential therapeutic target of novel inhibitors for treatment of inflammatory diseases | Mus musculus |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
5.3.99.3 | (5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate | Mus musculus | - |
(5Z,13E)-(15S)-11alpha,15-dihydroxy-9-oxoprosta-5,13-dienoate | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
5.3.99.3 | Mus musculus | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
5.3.99.3 | fibroblast cell line | - |
Mus musculus | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
5.3.99.3 | (5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate | - |
Mus musculus | (5Z,13E)-(15S)-11alpha,15-dihydroxy-9-oxoprosta-5,13-dienoate | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
5.3.99.3 | microsomal prostaglandin E synthase-1 | - |
Mus musculus |
5.3.99.3 | mPGES-1 | - |
Mus musculus |