EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.1.164 | ATP + L-seryl-tRNASec | Trypanosoma brucei | null mutants of PSTK abolish selenoprotein synthesis, demonstrating the essentiality of the enzyme for the formation of L-selenocysteinyl-tRNASec. Growth of the knockout strain is not impaired. Thus, unlike mammals, trypanosomes do not require selenoproteins for viability | ADP + O-phospho-L-seryl-tRNASec | - |
? | |
2.9.1.2 | O-phospho-L-seryl-tRNASec + selenophosphate | Trypanosoma brucei | null mutants of SepSecS abolish selenoprotein synthesis, demonstrating the essentiality of the enzyme for the formation of L-selenocysteinyl-tRNASec. Growth of the knockout strain is not impaired. Thus, unlike mammals, trypanosomes do not require selenoproteins for viability | L-selenocysteinyl-tRNASec + phosphate | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.7.1.164 | Trypanosoma brucei | - |
- |
- |
2.9.1.2 | Trypanosoma brucei | - |
- |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.1.164 | ATP + L-seryl-tRNASec | - |
Trypanosoma brucei | ADP + O-phospho-L-seryl-tRNASec | - |
? | |
2.7.1.164 | ATP + L-seryl-tRNASec | null mutants of PSTK abolish selenoprotein synthesis, demonstrating the essentiality of the enzyme for the formation of L-selenocysteinyl-tRNASec. Growth of the knockout strain is not impaired. Thus, unlike mammals, trypanosomes do not require selenoproteins for viability | Trypanosoma brucei | ADP + O-phospho-L-seryl-tRNASec | - |
? | |
2.9.1.2 | O-phospho-L-seryl-tRNASec + selenophosphate | - |
Trypanosoma brucei | L-selenocysteinyl-tRNASec + phosphate | - |
? | |
2.9.1.2 | O-phospho-L-seryl-tRNASec + selenophosphate | null mutants of SepSecS abolish selenoprotein synthesis, demonstrating the essentiality of the enzyme for the formation of L-selenocysteinyl-tRNASec. Growth of the knockout strain is not impaired. Thus, unlike mammals, trypanosomes do not require selenoproteins for viability | Trypanosoma brucei | L-selenocysteinyl-tRNASec + phosphate | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.7.1.164 | phosphoseryl-tRNASec kinase | - |
Trypanosoma brucei |
2.7.1.164 | PSTK | - |
Trypanosoma brucei |
2.9.1.2 | SepSecS | - |
Trypanosoma brucei |