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Literature summary extracted from

  • Jiang, X.; Lautermilch, N.J.; Watari, H.; Westenbroek, R.E.; Scheuer, T.; Catterall, W.A.
    Modulation of CaV2.1 channels by Ca2+/calmodulin-dependent protein kinase II bound to the C-terminal domain (2008), Proc. Natl. Acad. Sci. USA, 105, 341-346.
    View publication on PubMedView publication on EuropePMC

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.7.11.17 additional information CaMKII binds and enhances the activity of voltage-gated calcium 2.1 channels, but the modulation is not caused by phosphorylation Homo sapiens

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.11.17 autocamtide-2 related inhibitory peptide
-
 Homo sapiens
2.7.11.17 CaM-KIIN noncompetitive inhibitor Homo sapiens
2.7.11.17 KN-93
-
 Homo sapiens

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.7.11.17 Ca2+ dependent on Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.11.17 additional information Homo sapiens CaMKII regulates P/Q-type Ca2+ current in neurons ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.11.17 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.11.17 tsA-201 cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.11.17 additional information CaMKII regulates P/Q-type Ca2+ current in neurons Homo sapiens ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.11.17 calcium/calmodulin-dependent protein kinase II
-
 Homo sapiens
2.7.11.17 CaMKII
-
 Homo sapiens

Cofactor

EC Number Cofactor Comment Organism Structure
2.7.11.17 ATP
-
 Homo sapiens
2.7.11.17 Calmodulin dependent on Homo sapiens