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Literature summary extracted from

  • Newsome, J.J.; Colucci, M.A.; Hassani, M.; Beall, H.D.; Moody, C.J.
    Benzimidazole- and benzothiazole-quinones: excellent substrates for NAD(P)H:quinone oxidoreductase 1 (2007), Org. Biomol. Chem., 5, 3665-3673.
    View publication on PubMed

Application

EC Number Application Comment Organism
1.6.5.2 medicine synthesis of novel heterocyclic quinones (benzimidazole- and benzothiazole-quinones) as excellent substrates for recombinant human NQO1 Homo sapiens

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.6.5.2
-
 Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
1.6.5.2 Homo sapiens
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.6.5.2 2-acetoxymethyl-6-methoxy-1-methylbenzimidazole-4,7-dione + NADH
-
 Homo sapiens ? + NAD+
-
 ?
1.6.5.2 2-hydroxymethyl-5-methoxy-1-methylbenzimidazole-4,7-dione + NADH
-
 Homo sapiens ? + NAD+
-
 ?
1.6.5.2 2-hydroxymethyl-5-methoxybenzothiazole-4,7-dione + NADH
-
 Homo sapiens ? + NAD+
-
 ?
1.6.5.2 2-hydroxymethyl-6-methoxy-1-methylbenzimidazole-4,7-dione + NADH
-
 Homo sapiens ? + NAD+
-
 ?
1.6.5.2 5-methoxy-2-methylbenzothiazole-4,7-dione + NADH
-
 Homo sapiens ? + NAD+
-
 ?
1.6.5.2 6-methoxy-1-methyl-2-(4-nitrophenoxymethyl)benzimidazole-4,7-dione + NADH
-
 Homo sapiens ? + NAD+
-
 ?
1.6.5.2 6-methoxy-1-methylbenzimidazole-4,7-dione + NADH
-
 Homo sapiens ? + NAD+
-
 ?
1.6.5.2 menadione + NADH
-
 Homo sapiens reduced menadione + NAD+
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.6.5.2 DT-diaphorase
-
 Homo sapiens
1.6.5.2 NAD(P)H:quinone oxidoreductase 1
-
 Homo sapiens
1.6.5.2 NQO1
-
 Homo sapiens