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Literature summary extracted from

  • Otani, H.; Okumura, A.; Nagai, K.; Okumura, N.
    Colocalization of a carnosine-splitting enzyme, tissue carnosinase (CN2)/cytosolic non-specific dipeptidase 2 (CNDP2), with histidine decarboxylase in the tuberomammillary nucleus of the hypothalamus (2008), Neurosci. Lett., 445, 166-169.
    View publication on PubMed

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.4.13.20 cytosol
-
 Rattus norvegicus 5829
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.1.1.22 additional information Rattus norvegicus HDC is the key enzyme for histamine biosynthesis ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.4.13.20 Rattus norvegicus
-
-
-
4.1.1.22 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.13.20 hypothalamus in the tuberomammillary nucleus of the hypothalamus Rattus norvegicus
-
4.1.1.22 hypothalamus tuberomammillary nucleus of the hypothalamus Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.13.20 beta-Ala-L-His + H2O i.e. L-carnosine Rattus norvegicus beta-Ala + L-His
-
 ?
4.1.1.22 L-histidine
-
 Rattus norvegicus histamine + CO2
-
 ?
4.1.1.22 additional information HDC is the key enzyme for histamine biosynthesis Rattus norvegicus ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.4.13.20 CN2
-
 Rattus norvegicus
3.4.13.20 CNDP dipeptidase 2
-
 Rattus norvegicus
3.4.13.20 CNDP2
-
 Rattus norvegicus
3.4.13.20 cytosolic non-specific dipeptidase 2
-
 Rattus norvegicus
3.4.13.20 tissue carnosinase
-
 Rattus norvegicus

Cofactor

EC Number Cofactor Comment Organism Structure
4.1.1.22 pyridoxal 5'-phosphate
-
 Rattus norvegicus