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Literature summary extracted from

  • Wang, L.; Nair, A.K.; Menon, K.M.
    Ribonucleic acid binding protein-mediated regulation of luteinizing hormone receptor expression in granulosa cells: relationship to sterol metabolism (2007), Mol. Endocrinol., 21, 2233-2241.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.1.36 25-hydroxycholesterol expression of mevalonate kinase is regulated by sterol response element-binding protein-1, which is sensitive to the cllular concentration of 25-hydroxycholesterol. Presence of 25-hydroxycholesterol inhibits mevalonate kinase expression and subsequently its binding to luteinizing hormone receptor mRNA Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.1.36 additional information Homo sapiens mevalonate kinase is directly involved in regulation of luteinizing hormone receptor expression ?
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 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.1.36 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.1.36 granulosa cell cultured granulosa cell Homo sapiens
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Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.1.36 additional information mevalonate kinase is directly involved in regulation of luteinizing hormone receptor expression Homo sapiens ?
-
 ?