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Literature summary extracted from

  • Backs, J.; Backs, T.; Bezprozvannaya, S.; McKinsey, T.A.; Olson, E.N.
    Histone deacetylase 5 acquires calcium/calmodulin-dependent kinase II responsiveness by oligomerization with histone deacetylase 4 (2008), Mol. Cell. Biol., 28, 3437-3445.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.7.11.17 expression in COS cells Mus musculus

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.7.11.17 Ca2+ dependent on Mus musculus

Organism

EC Number Organism UniProt Comment Textmining
2.7.11.17 Mus musculus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.11.17 C2C12 cell
-
 Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.11.17 ATP + histone deacetylase 4
-
 Mus musculus ADP + phosphorylated histone deacetylase 4
-
 ?
2.7.11.17 ATP + histone deacetylase 5 whereas histone deacetylase 5 alone is unresponsive to CaMKII, it becomes responsive to CaMKII in the presence of histone deacetylase 4 Mus musculus ADP + phosphorylated histone deacetylase 5
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.11.17 calcium/calmodulin-dependent protein kinase II
-
 Mus musculus
2.7.11.17 CaMKII
-
 Mus musculus

Cofactor

EC Number Cofactor Comment Organism Structure
2.7.11.17 ATP
-
 Mus musculus
2.7.11.17 Calmodulin dependent on Mus musculus