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Literature summary extracted from

  • Rissland, O.S.; Mikulasova, A.; Norbury, C.J.
    Efficient RNA polyuridylation by noncanonical poly(A) polymerases (2007), Mol. Cell. Biol., 27, 3612-3624.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.7.7.19 expressed in 293T cells Homo sapiens
2.7.7.19 expressed in Escherichia coli BL21(DE3) pLysS cells Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.7.7.19 cytoplasm
-
 Homo sapiens 5737
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.7.19 ATP + RNA Homo sapiens
-
 diphosphate + RNA(A)n
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.7.19 Homo sapiens
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.7.7.19 native tandem affinity column chromatography Homo sapiens
2.7.7.19 Sepharose column chromatography Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.7.19 ATP + RNA
-
 Homo sapiens diphosphate + RNA(A)n
-
 ?
2.7.7.19 ATP + RNA Hs2 complexes have very little PAP activity, Hs2 also displays efficient poly(U) polymerase activity Homo sapiens diphosphate + RNA(A)n
-
 ?
2.7.7.19 UTP + RNA recombinant Cid1 shows a preference for UTP over ATP, the poly(U) polymerase activity of recombinant Cid1 out-competes its PAP activity under physiologically relevant conditions Homo sapiens diphosphate + RNA(U)n
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.7.19 Cid1 putative cytoplasmic PAP, in addition to having PAP activity, Cid1 possesses substantial poly(U) polymerase activity Homo sapiens
2.7.7.19 Hs2 contains two PAP-associated domains and two nucleotidyl transferase motifs Homo sapiens
2.7.7.19 PAP
-
 Homo sapiens
2.7.7.19 poly(A) polymerase
-
 Homo sapiens
2.7.7.19 ZCCHC6
-
 Homo sapiens