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Literature summary extracted from

  • Shen, D.K.; Filopon, D.; Chaker, H.; Boullanger, S.; Derouazi, M.; Polack, B.; Toussaint, B.
    High-cell-density regulation of the Pseudomonas aeruginosa type III secretion system: implications for tryptophan catabolites (2008), Microbiology, 154, 2195-2208.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.2.1.20 L-serine + 1-C-(indol-3-yl)glycerol 3-phosphate Pseudomonas aeruginosa Trp is a precursor of several important signalling molecules in Pseudomonas spp., overview L-tryptophan + glyceraldehyde 3-phosphate + H2O
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 ?
4.2.1.20 additional information Pseudomonas aeruginosa the enzyme is involved in regulation/inhibition of Pseudomonas aeruginosa type III secretion system, T3SS, by inhibition of T3SS expression through tryptophan catabolites, overview. The T3SS system consists of 43 coordinately regulated genes encoding type III secretion and translocation machinery, regulatory factors, type III effectors and effector-specific chaperones ?
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Organism

EC Number Organism UniProt Comment Textmining
4.2.1.20 Pseudomonas aeruginosa
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 strains CHA or PAO1
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Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.2.1.20 L-serine + 1-C-(indol-3-yl)glycerol 3-phosphate
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 Pseudomonas aeruginosa L-tryptophan + glyceraldehyde 3-phosphate + H2O
-
 ?
4.2.1.20 L-serine + 1-C-(indol-3-yl)glycerol 3-phosphate Trp is a precursor of several important signalling molecules in Pseudomonas spp., overview Pseudomonas aeruginosa L-tryptophan + glyceraldehyde 3-phosphate + H2O
-
 ?
4.2.1.20 additional information the enzyme is involved in regulation/inhibition of Pseudomonas aeruginosa type III secretion system, T3SS, by inhibition of T3SS expression through tryptophan catabolites, overview. The T3SS system consists of 43 coordinately regulated genes encoding type III secretion and translocation machinery, regulatory factors, type III effectors and effector-specific chaperones Pseudomonas aeruginosa ?
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 ?