Literature summary extracted from
Zhu, M.M.; Skraly, F.A.; Cameron, D.C.
Accumulation of methylglyoxal in anaerobically grown Escherichia coli and its detoxification by expression of the Pseudomonas putida glyoxalase I gene. (2001), Metab. Eng., 3, 218-225.
Activating Compound
EC Number |
Activating Compound |
Comment |
Organism |
Structure |
---|
4.4.1.5 |
additional information |
activity of glyoxalase I in transgenic Escherichia coli with Pseudomonas putida glyoxalase I under anaerobic conditions is 12fold higher than that in control cells |
Pseudomonas putida |
|
Application
EC Number |
Application |
Comment |
Organism |
---|
4.4.1.5 |
additional information |
compared to control cells, transgenic cells with Pseudomonas putida glyoxalase I display a significant reduction of 35-43% in intracellular methylglyoxal and a significant decrease of 30% in extracellular methylglyoxal. Expression of Pseudomonas putida glyoxalase I in transgenic Escherichia coli markedly improves cell growth and results in a 50% increase in 1,3-propanediol production |
Pseudomonas putida |
Cloned(Commentary)
EC Number |
Cloned (Comment) |
Organism |
---|
4.4.1.5 |
expressed in transgenic Escherichia coli |
Pseudomonas putida |
Organism
EC Number |
Organism |
UniProt |
Comment |
Textmining |
---|
4.4.1.5 |
Pseudomonas putida |
P16635 |
- |
- |
Synonyms
EC Number |
Synonyms |
Comment |
Organism |
---|
4.4.1.5 |
glyoxalase I |
- |
Pseudomonas putida |