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Literature summary extracted from

  • Arias, A.; Arnold, J.J.; Sierra, M.; Smidansky, E.; Domingo, E.; Cameron, C.E.
    Determinants of RNA-dependent RNA polymerase (in)fidelity revealed by kinetic analysis of the polymerase encoded by a foot-and-mouth disease virus mutant with reduced sensitivity to ribavirin (2008), J. Virol., 82, 12346-12355.
    View publication on PubMedView publication on EuropePMC

Protein Variants

EC Number Protein Variants Comment Organism
2.7.7.48 M296I the mutant exhibits reduced sensitivity to ribavirin Foot-and-mouth disease virus

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.7.48 ribavirin
-
 Foot-and-mouth disease virus

Organism

EC Number Organism UniProt Comment Textmining
2.7.7.48 Foot-and-mouth disease virus
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.7.48 nucleoside triphosphate + RNAn
-
 Foot-and-mouth disease virus diphosphate + RNAn+1
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.7.48 3Dpol
-
 Foot-and-mouth disease virus
2.7.7.48 RNA-dependent RNA polymerase
-
 Foot-and-mouth disease virus