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Literature summary extracted from

  • Atta-ur-Rahman, F.A.; Zareen, S.; Choudhary, M.I.; Akhtar, M.N.; Khan, S.N.
    alpha-Glucosidase inhibitory activity of triterpenoids from Cichorium intybus (2008), J. Nat. Prod., 71, 910-913.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.2.1.20 (3beta,18alpha,21alpha)-urs-20(30)-ene-3,21-diyl-diacetate diacetate derivative, good alpha-glucosidase inhibitory activity Saccharomyces cerevisiae
3.2.1.20 17-epi-methyl-6-hydroxyangolensate intybusoloid, triterpenoid from Cichorium intybus, methanolic extract of seeds Saccharomyces cerevisiae
3.2.1.20 18alpha,19beta-20(30)-taraxasten-3beta,21alpha-diol cichoridiol, triterpenoid from Cichorium intybus, methanolic extract of seeds, good alpha-glucosidase inhibitory activity Saccharomyces cerevisiae
3.2.1.20 6,7-dihydroxycoumarin
-
 Saccharomyces cerevisiae
3.2.1.20 beta-sitosterol
-
 Saccharomyces cerevisiae
3.2.1.20 betulin
-
 Saccharomyces cerevisiae
3.2.1.20 betulinaldehyde
-
 Saccharomyces cerevisiae
3.2.1.20 betulinic acid
-
 Saccharomyces cerevisiae
3.2.1.20 deoxynojirimycin
-
 Saccharomyces cerevisiae
3.2.1.20 friedelin
-
 Saccharomyces cerevisiae
3.2.1.20 lupeol
-
 Saccharomyces cerevisiae
3.2.1.20 methyl-alpha-D-galactopyranoside
-
 Saccharomyces cerevisiae
3.2.1.20 stigmasterol
-
 Saccharomyces cerevisiae
3.2.1.20 syringic acid
-
 Saccharomyces cerevisiae
3.2.1.20 vanillic acid good alpha-glucosidase inhibitory activity Saccharomyces cerevisiae

Organism

EC Number Organism UniProt Comment Textmining
3.2.1.20 Saccharomyces cerevisiae
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.2.1.20 4-nitrophenyl alpha-D-glucopyranoside + H2O
-
 Saccharomyces cerevisiae 4-nitrophenol + alpha-D-glucopyranose
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.2.1.20 alpha-glucosidase
-
 Saccharomyces cerevisiae

IC50 Value

EC Number IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
3.2.1.20 0.01
-
-
 Saccharomyces cerevisiae (3beta,18alpha,21alpha)-urs-20(30)-ene-3,21-diyl-diacetate
3.2.1.20 0.0519
-
-
 Saccharomyces cerevisiae 18alpha,19beta-20(30)-taraxasten-3beta,21alpha-diol
3.2.1.20 0.069
-
-
 Saccharomyces cerevisiae vanillic acid
3.2.1.20 0.321
-
-
 Saccharomyces cerevisiae friedelin
3.2.1.20 0.425
-
-
 Saccharomyces cerevisiae deoxynojirimycin