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Literature summary extracted from
- Microsomal prostaglandin E synthase-1 inhibition in cardiovascular inflammatory disease (2008), J. Intern. Med., 263, 500-505.
Application
| EC Number | Application | Comment | Organism |
|---|---|---|---|
| 5.3.99.3 | medicine | mPGES-1 inhibitors have therapeutic potential in syndromes of cardiovascular inflammation, cancer and perhaps neurodegenerative disease | Mus musculus |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 5.3.99.3 | (5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate | Mus musculus | - |
(5Z,13E)-(15S)-11alpha,15-dihydroxy-9-oxoprosta-5,13-dienoate | - |
? |  |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 5.3.99.3 | Mus musculus | - |
- |
- |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 5.3.99.3 | (5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate | - |
Mus musculus | (5Z,13E)-(15S)-11alpha,15-dihydroxy-9-oxoprosta-5,13-dienoate | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 5.3.99.3 | microsomal prostaglandin E synthase-1 | - |
Mus musculus |
| 5.3.99.3 | mPGES-1 | - |
Mus musculus |
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Release 2023.1 (January 2023)
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