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Literature summary extracted from

  • Wang, L.; Zhou, X.; Zhou, T.; Ma, D.; Chen, S.; Zhi, X.; Yin, L.; Shao, Z.; Ou, Z.; Zhou, P.
    Ecto-5'-nucleotidase promotes invasion, migration and adhesion of human breast cancer cells (2008), J. Cancer Res. Clin. Oncol., 134, 365-372.
    View publication on PubMed

Application

EC Number Application Comment Organism
3.1.3.5 medicine CD73 may facilitate the adhesion, migration, and invasion of human breast cancer cells through its enzyme activity of generating adenosine Homo sapiens

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.3.5 adenosine 5'-(alpha,beta-methylene)diphosphate
-
 Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
3.1.3.5 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.3.5 breast cancer cell
-
 Homo sapiens
-
3.1.3.5 MDA-MB-231 cell
-
 Homo sapiens
-
3.1.3.5 T-47D cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.3.5 5'-AMP + H2O best substrate Homo sapiens adenosine + phosphate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.1.3.5 5'-NT
-
 Homo sapiens
3.1.3.5 CD73
-
 Homo sapiens
3.1.3.5 ecto 5'-nucleotidase
-
 Homo sapiens
3.1.3.5 ecto-5-NT
-
 Homo sapiens