EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.8.4.1 | CH3-S-CoM + HS-CoB | Methanothermobacter marburgensis | - |
CoM-S-S-CoB + methane | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.8.4.1 | Methanothermobacter marburgensis | - |
strain DSM 2133, gene mcrA | - |
EC Number | Purification (Comment) | Organism |
---|---|---|
2.8.4.1 | active native enzyme to homogeneity | Methanothermobacter marburgensis |
EC Number | Reaction | Comment | Organism | Reaction ID |
---|---|---|---|---|
2.8.4.1 | methyl-CoM + CoB = CoM-S-S-CoB + methane | reaction mechanism, different varaints, the Ni(I) center is assumed to attack the thioether sulfur of CH3-S-CoM, generating -CH3 and the thiolate complex CoM-SNi(II)F430 as intermediates, detailed overview | Methanothermobacter marburgensis |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.8.4.1 | CH3-S-CoM + HS-CoB | - |
Methanothermobacter marburgensis | CoM-S-S-CoB + methane | - |
? | |
2.8.4.1 | CH3-S-CoM + HS-CoB | i.e. methyl-coenzyme M + coenzyme B | Methanothermobacter marburgensis | CoM-S-S-CoB + methane | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.8.4.1 | MCR | - |
Methanothermobacter marburgensis |
2.8.4.1 | methyl-coenzyme M reductase A | - |
Methanothermobacter marburgensis |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
2.8.4.1 | F-430 | with Ni(I) oxidation state | Methanothermobacter marburgensis |