Literature summary extracted from
Del Papa, M.F.; Perego, M.
Ethanolamine activates a sensor histidine kinase regulating its utilization in Enterococcus faecalis (2008), J. Bacteriol., 190, 7147-7156.
Activating Compound
EC Number |
Activating Compound |
Comment |
Organism |
Structure |
---|
2.7.13.3 |
ethanolamine |
induces a 15fold increase in the rate of autophosphorylation in vitro of the HK17 sensor histidine kinase |
Enterococcus faecalis |
|
Cloned(Commentary)
EC Number |
Cloned (Comment) |
Organism |
---|
2.7.13.3 |
cloning of the RR-HK17 TCS system from strain V583 |
Enterococcus faecalis |
Protein Variants
EC Number |
Protein Variants |
Comment |
Organism |
---|
2.7.13.3 |
additional information |
ethanolamine utilization and growth on it is abolished in the response regulator RR17 mutant strain lacking a functional partner of histidine kinase in the RR-HK17 two-component system, phenotype, overview |
Enterococcus faecalis |
Localization
EC Number |
Localization |
Comment |
Organism |
GeneOntology No. |
Textmining |
---|
2.7.13.3 |
cytoplasm |
- |
Enterococcus faecalis |
5737 |
- |
Metals/Ions
EC Number |
Metals/Ions |
Comment |
Organism |
Structure |
---|
2.7.13.3 |
Mg2+ |
- |
Enterococcus faecalis |
|
Natural Substrates/ Products (Substrates)
EC Number |
Natural Substrates |
Organism |
Comment (Nat. Sub.) |
Natural Products |
Comment (Nat. Pro.) |
Rev. |
Reac. |
---|
2.7.13.3 |
additional information |
Enterococcus faecalis |
the sensory histidine kinase acts in the two-component system with the response regulator as RR-HK17, EF1633-EF1632, in the regulation of ethanolamine utilization, which can be the sole carbon source for the organism, mechanism, overview |
? |
- |
? |
|
Organism
EC Number |
Organism |
UniProt |
Comment |
Textmining |
---|
2.7.13.3 |
Enterococcus faecalis |
- |
human clinical isolate |
- |
Posttranslational Modification
EC Number |
Posttranslational Modification |
Comment |
Organism |
---|
2.7.13.3 |
phosphoprotein |
the enzyme HK17 performs autophosphorylation stimulated by ethanolamine |
Enterococcus faecalis |
Substrates and Products (Substrate)
EC Number |
Substrates |
Comment Substrates |
Organism |
Products |
Comment (Products) |
Rev. |
Reac. |
---|
2.7.13.3 |
additional information |
the sensory histidine kinase acts in the two-component system with the response regulator as RR-HK17, EF1633-EF1632, in the regulation of ethanolamine utilization, which can be the sole carbon source for the organism, mechanism, overview |
Enterococcus faecalis |
? |
- |
? |
|
Subunits
EC Number |
Subunits |
Comment |
Organism |
---|
2.7.13.3 |
More |
the N-terminus of HK17 forms a GAF domain, structure of the RR-HK17 two-component system |
Enterococcus faecalis |
Synonyms
EC Number |
Synonyms |
Comment |
Organism |
---|
2.7.13.3 |
HK17 |
- |
Enterococcus faecalis |
2.7.13.3 |
sensory histidine kinase |
- |
Enterococcus faecalis |
Temperature Optimum [°C]
EC Number |
Temperature Optimum [°C] |
Temperature Optimum Maximum [°C] |
Comment |
Organism |
---|
2.7.13.3 |
22 |
- |
assay at room temperature |
Enterococcus faecalis |
pH Optimum
EC Number |
pH Optimum Minimum |
pH Optimum Maximum |
Comment |
Organism |
---|
2.7.13.3 |
7.5 |
- |
assay at |
Enterococcus faecalis |
Cofactor
EC Number |
Cofactor |
Comment |
Organism |
Structure |
---|
2.7.13.3 |
ATP |
- |
Enterococcus faecalis |
|