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Literature summary extracted from
- Roles of the sortases of Streptococcus pneumoniae in assembly of the RlrA pilus (2008), J. Bacteriol., 190, 6002-6013.
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.4.22.B63 | additional information | Streptococcus pneumoniae | SrtC-1, SrtC-2, and SrtC-3 are responsible for RlrA pilus assembly and exhibit functional redundancy with respect to backbone assembly and cell wall localization. SrtC-3 is required for the incorporation of the accessory subunits RrgA and RrgC. Deleterious effect on pilus assembly upon alteration of the cell wall sorting signals of the accessory subunit proteins | ? | - |
? |  |
| 3.4.22.70 | additional information | Streptococcus pneumoniae | SrtA is dispensable for pilus assembly and localization to the cell wall | ? | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.4.22.B63 | Streptococcus pneumoniae | - |
- |
- |
| 3.4.22.70 | Streptococcus pneumoniae | - |
- |
- |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.4.22.B63 | additional information | SrtC-1, SrtC-2, and SrtC-3 are responsible for RlrA pilus assembly and exhibit functional redundancy with respect to backbone assembly and cell wall localization. SrtC-3 is required for the incorporation of the accessory subunits RrgA and RrgC. Deleterious effect on pilus assembly upon alteration of the cell wall sorting signals of the accessory subunit proteins | Streptococcus pneumoniae | ? | - |
? | |
| 3.4.22.70 | additional information | SrtA is dispensable for pilus assembly and localization to the cell wall | Streptococcus pneumoniae | ? | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 3.4.22.B63 | SrtC-1 | - |
Streptococcus pneumoniae |
| 3.4.22.B63 | SrtC-2 | - |
Streptococcus pneumoniae |
| 3.4.22.B63 | SrtC-3 | - |
Streptococcus pneumoniae |
| 3.4.22.70 | SrtA | - |
Streptococcus pneumoniae |
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