EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
4.2.3.22 | Mg2+ | - |
Streptomyces coelicolor |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
4.2.3.22 | additional information | Streptomyces coelicolor | catalyzes the Mg2+-dependent cyclization of conversion of farnesyl diphosphate to a mixture of germacradienol, germacrene D, and geosmin, accompanied by small amounts of octalin | ? | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
4.1.99.16 | Streptomyces coelicolor | Q9X839 | C-terminal domain; germacradienol/germacrene D synthase | - |
4.2.3.22 | Streptomyces coelicolor | - |
- |
- |
EC Number | Reaction | Comment | Organism | Reaction ID |
---|---|---|---|---|
4.1.99.16 | (1E,4S,5E,7R)-germacra-1(10),5-dien-11-ol + H2O = (-)-geosmin + acetone | conversion of germacradienol to geosmin results in the release of the three-carbon side chain as acetone and involves a 1,2-hydride shift of the bridgehead hydrogen exclusively into ring B of geosmin | Streptomyces coelicolor |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
4.1.99.16 | (1E,4S,5E,7R)-germacra-1(10),5-dien-11-ol + H2O | catalysed by the C-terminal domain of the bifunctional enzyme | Streptomyces coelicolor | (-)-geosmin + acetone | - |
? | |
4.1.99.16 | additional information | conversion of germacradienol to geosmin results in the release of the three-carbon side chain as acetone and involves a 1,2-hydride shift of the bridgehead hydrogen exclusively into ring B of geosmin | Streptomyces coelicolor | ? | - |
? | |
4.2.3.22 | additional information | catalyzes the Mg2+-dependent cyclization of conversion of farnesyl diphosphate to a mixture of germacradienol, germacrene D, and geosmin, accompanied by small amounts of octalin | Streptomyces coelicolor | ? | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
4.2.3.22 | germacradienol synthase | - |
Streptomyces coelicolor |
4.2.3.22 | germacradienol/geosmin synthase | - |
Streptomyces coelicolor |