Literature summary extracted from

Oikawa, H.; Toyomasu, T.; Toshima, H.; Ohashi, S.; Kawaide, H.; Kamiya, Y.; Ohtsuka, M.; Shinoda, S.; Mitsuhashi, W.; Sassa, T.
Cloning and functional expression of cDNA encoding aphidicolan-16 beta-ol synthase: A key enzyme responsible for formation of an unusual diterpene skeleton in biosynthesis of aphidicolin (2001), J. Am. Chem. Soc., 123, 5154-5155.

Cloned(Commentary)

EC Number	Cloned (Comment)	Organism
4.2.3.42	bifunctional enzyme which also has EC 5.5.1.14, syn-copalyl diphosphate synthase activity	Neocamarosporium betae

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
4.2.3.42	9alpha-copalyl diphosphate + H2O	Neocamarosporium betae	bifunctional enzyme which also has EC 5.5.1.14, syn-copalyl diphosphate synthase activity	aphidicolan-16beta-ol + diphosphate	-	?

Organism

EC Number	Organism	UniProt	Comment	Textmining
4.2.3.42	Neocamarosporium betae	Q96WT2	bifunctional enzyme which also has EC 5.5.1.14 syn-copalyl diphosphate synthase activity	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
4.2.3.42	9alpha-copalyl diphosphate + H2O	bifunctional enzyme which also has EC 5.5.1.14, syn-copalyl diphosphate synthase activity	Neocamarosporium betae	aphidicolan-16beta-ol + diphosphate	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
4.2.3.42	PbACS	bifunctional enzyme which also has EC 5.5.1.14 syn-copalyl diphosphate synthase activity	Neocamarosporium betae

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Release 2023.1 (January 2023)