EC Number | Cloned (Comment) | Organism |
---|---|---|
4.3.1.7 | overexpression in Escherichia coli | Salmonella enterica subsp. enterica serovar Typhimurium |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
4.3.1.7 | Co2+ | cobalt-carbon bond cleavage depends obligatorily on substrate binding in all adenosylcobalamin-dependent enzymes, with the exception of ribonucleotide triphosphate reductase, which can cleave the bond upon binding a nucleotide triphosphate activator | Salmonella enterica subsp. enterica serovar Typhimurium |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
4.3.1.7 | 500000 | - |
calculated holoenzyme molecular mass | Salmonella enterica subsp. enterica serovar Typhimurium |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
4.3.1.7 | ethanolamine | Salmonella enterica subsp. enterica serovar Typhimurium | The family of vitamin B12 coenzyme-dependent enzymes catalyzes the radical-mediated cleavage of unactivated C-H bonds and associated 1,2-cross-migrations of hydrogen and alkyl, carbonyl, hydroxyl, or amino groups | acetaldehyde + NH3 | - |
ir | |
4.3.1.7 | additional information | Salmonella enterica subsp. enterica serovar Typhimurium | the radical intermediate is a substrate radical | ? | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
4.3.1.7 | Salmonella enterica subsp. enterica serovar Typhimurium | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
4.3.1.7 | - |
Salmonella enterica subsp. enterica serovar Typhimurium |
EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
4.3.1.7 | additional information | - |
activity of the purified enzyme with aminoethanol as substrate is 20-30 micromol/min/mg. | Salmonella enterica subsp. enterica serovar Typhimurium |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
4.3.1.7 | ethanolamine | The family of vitamin B12 coenzyme-dependent enzymes catalyzes the radical-mediated cleavage of unactivated C-H bonds and associated 1,2-cross-migrations of hydrogen and alkyl, carbonyl, hydroxyl, or amino groups | Salmonella enterica subsp. enterica serovar Typhimurium | acetaldehyde + NH3 | - |
ir | |
4.3.1.7 | additional information | the radical intermediate is a substrate radical | Salmonella enterica subsp. enterica serovar Typhimurium | ? | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
4.3.1.7 | ethanolamine ammonia-lyase | - |
Salmonella enterica subsp. enterica serovar Typhimurium |
4.3.1.7 | ethanolamine deaminase | - |
Salmonella enterica subsp. enterica serovar Typhimurium |
EC Number | Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
4.3.1.7 | 22 | - |
ethanolamine | at 0°C | Salmonella enterica subsp. enterica serovar Typhimurium | |
4.3.1.7 | 55 | - |
ethanolamine | at 22 °C | Salmonella enterica subsp. enterica serovar Typhimurium |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
4.3.1.7 | 7.45 | - |
assay at | Salmonella enterica subsp. enterica serovar Typhimurium |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
4.3.1.7 | adenosylcobalamin | vitamine B12 coenzyme | Salmonella enterica subsp. enterica serovar Typhimurium |