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Literature summary extracted from

  • Ticha, E.; Polakovicova, V.; Obernauerova, M.
    Regulation of phosphatidylglycerolphosphate synthase in aerobic yeast Kluyveromyces lactis (2008), Folia Microbiol. (Praha), 53, 319-324.
    View publication on PubMed

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.7.8.5 mitochondrion
-
 Kluyveromyces lactis 5739
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Organism

EC Number Organism UniProt Comment Textmining
2.7.8.5 Kluyveromyces lactis Q874C6 aerobic yeast, strain JBD100
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Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
2.7.8.5 additional information NetPhos 2.0 predicted motifs at residues Ser13, Thr9, and Tyr4 for protein kinase A and C (high score of 0.8), casein kinase I and II, glycogen-synthase kinase 3, Ca2+-calmodulin-dependent kinase II Kluyveromyces lactis

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.8.5 growth phase culture similar mRNA levels in cells progressing from exponential to stationary phase when grown on glucose, glycerol and/or ethanol as C source and in presence or absence of phospholipid precursors myo-inositol and/or choline Kluyveromyces lactis
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Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.7.8.5 0.00127
-
 30% decrease in activity in cells grown in presence of myo-inositol (1 h, 75 microM), mitochondrial extracts Kluyveromyces lactis
2.7.8.5 0.0018
-
 mitochondrial extracts Kluyveromyces lactis

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.8.5 CDP-1,2-diacyl-sn-glycerol + sn-glycerol 3-phosphate 20 min, 30°C, Mes-HCl pH 7, 1 mM Triton X-100, 0.3 mM MnCl2 Kluyveromyces lactis phosphatidylglycerophosphate + CMP
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.8.5 PGS1
-
 Kluyveromyces lactis
2.7.8.5 PGS1 KlPGS1: PGS1 gene from Kluyveromyces lactis Kluyveromyces lactis
2.7.8.5 Pgs1p
-
 Kluyveromyces lactis
2.7.8.5 phosphatidylglycerolphosphate synthase
-
 Kluyveromyces lactis