Literature summary extracted from

Pfleger, C.M.; Harvey, K.F.; Yan, H.; Hariharan, I.K.
Mutation of the gene encoding the ubiquitin activating enzyme Uba1 causes tissue overgrowth in Drosophila (2008), Fly, 1, 95-105.

Cloned(Commentary)

EC Number	Cloned (Comment)	Organism
6.2.1.45	expressed in Escherichia coli BL21(DE3) cells	Drosophila melanogaster

Protein Variants

EC Number	Protein Variants	Comment	Organism
6.2.1.45	additional information	a mutational reduction in Uba1 function (Uba1B2 mutation) reduces the efficacy of cell death, a complete loss of Uba1 function (Uba1A1 mutation) results in poor survival of mutant tissue and overgrowth of adjacent wild type tissue	Drosophila melanogaster

Organism

EC Number	Organism	UniProt	Comment	Textmining
6.2.1.45	Drosophila melanogaster	-	-	-

Purification (Commentary)

EC Number	Purification (Comment)	Organism
6.2.1.45	Ni-NTA column chromatography	Drosophila melanogaster

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
6.2.1.45	eye	-	Drosophila melanogaster	-

Synonyms

EC Number	Synonyms	Comment	Organism
6.2.1.45	Uba1	-	Drosophila melanogaster
6.2.1.45	ubiquitin protein ligase E1	-	Drosophila melanogaster

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Release 2023.1 (January 2023)