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Literature summary extracted from

  • Bianchi, M.; Amendola, R.; Federico, R.; Polticelli, F.; Mariottin, P.
    Two short protein domains are responsible for the nuclear localization of the mouse spermine oxidase mu isoform (2005), FEBS J., 272, 3052-3059.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.5.3.16 expression of mutant mSMOmuDELTA (with a deletion of the nuclear domain) in Escherichia coli Mus musculus

Protein Variants

EC Number Protein Variants Comment Organism
1.5.3.16 additional information purified mutant mSMOmuDELTA (with a deletion of the nuclear domain A) exhibits biochemical properties very similar to that of mSMOalpha and mSMOmu, in particular a pH optimum of 8.5 in 0.1 m Na-phosphate buffer, a Km value of 0.222 mM and a kcat value of 0.0208 per sec. Removal of the nuclear domain amino acid region abolishes proper nuclear targeting of the mSMOmu isoform Mus musculus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.5.3.16 0.22
-
 spermine pH 8.5, mutant mSMOmuDELTA (with a deletion of the nuclear domain A) Mus musculus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.5.3.16 cytosol splice variant mSMOmu is present in both nuclear and cytoplasmic compartments, two short protein domains are responsible for the nuclear localization of splice variant mSMOmu Mus musculus 5829
-
1.5.3.16 nucleus splice variant mSMOmu is present in both nuclear and cytoplasmic compartments, two short protein domains are responsible for the nuclear localization of splice variant mSMOmu Mus musculus 5634
-

Organism

EC Number Organism UniProt Comment Textmining
1.5.3.16 Mus musculus Q99K82
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.5.3.16 recombinantly produced mSMOmuDELTA (with a deletion of the nuclear domain) Mus musculus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.5.3.16 spermine + O2 + H2O mutant mSMOmuDELTA (with a deletion of the nuclear domain A) is not active on spermidine, N1-acetylspermidine or N1-acetylspermine Mus musculus ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.5.3.16 mSMOmu splice variant Mus musculus

Turnover Number [1/s]

EC Number Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
1.5.3.16 0.0208
-
 spermine pH 8.5, mutant mSMOmuDELTA (with a deletion of the nuclear domain A) Mus musculus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.5.3.16 8.5
-
 mutant mSMOmuDELTA (with a deletion of the nuclear domain) Mus musculus