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Literature summary extracted from
- T4 endonuclease V: review and application to dermatology (2008), Expert. Opin. Biol. Ther., 8, 829-838.
Application
| EC Number | Application | Comment | Organism |
|---|---|---|---|
| 3.1.21.7 | medicine | in xeroderma pigmentosum patients, topical application of liposome-encapsulated T4 endonuclease V reduces the incidence of basal cell carcinomas by 30% and of actinic keratoses by more than 68% | Tequatrovirus T4 |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.1.21.7 | Tequatrovirus T4 | - |
- |
- |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.1.21.7 | DNA + H2O | endonuclease V repairs UV-induced cyclobutane pyrimidine dimers in DNA | Tequatrovirus T4 | 5'-phosphoryltermini DNA + 3'-hydroxyltermini DNA | - |
? |  |
| 3.1.21.7 | double-stranded plasmid DNA + H2O | - |
Tequatrovirus T4 | nicked circular DNA + linearized DNA | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 3.1.21.7 | endonuclease V | - |
Tequatrovirus T4 |
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