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Literature summary extracted from

  • Mukai, A.; Hashimoto, N.
    Localized cyclic AMP-dependent protein kinase activity is required for myogenic cell fusion (2008), Exp. Cell Res., 314, 387-397.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.7.11.11 forskolin 0.024 mM, forskolin enhances lamellipodium formation where active PKA is accumulated Mus musculus

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.11.11 H-89
-
 Mus musculus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.7.11.11 lamellipodium
-
 Mus musculus 30027
-

Organism

EC Number Organism UniProt Comment Textmining
2.7.11.11 Mus musculus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.11.11 COM-3 cell
-
 Mus musculus
-
2.7.11.11 myoblast
-
 Mus musculus
-
2.7.11.11 myoblast cell line
-
 Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.11.11 additional information localized PKA activity is required for fusion of mononucleated myoblasts and plays a pivotal role in the early steps of myogenic cell fusion Mus musculus ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.11.11 PKA
-
 Mus musculus
2.7.11.11 protein kinase A
-
 Mus musculus

Cofactor

EC Number Cofactor Comment Organism Structure
2.7.11.11 ATP
-
 Mus musculus
2.7.11.11 cAMP dependent Mus musculus