EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
3.1.1.4 | 1,3,5-trihydroxybenzene | potent inhibition of enzymatic activity and endemic activity of PLA2, binding structure, overview | Crotalus adamanteus | |
3.1.1.4 | 1,3-dihydroxy benzene | potent inhibition of enzymatic activity and endemic activity of PLA2, binding structure, overview | Crotalus adamanteus | |
3.1.1.4 | 2,4,6-trihydroxy acetophenone | potent inhibition of enzymatic activity and endemic activity of PLA2, binding structure, overview | Crotalus adamanteus | |
3.1.1.4 | 2,4-dihydroxy acetophenone | binding structure, overview | Crotalus adamanteus | |
3.1.1.4 | 2,6-dihydroxy acetophenone | binding structure, overview | Crotalus adamanteus | |
3.1.1.4 | additional information | molecular modeling of the inhibition mechanism of polyhydroxylated phenols | Crotalus adamanteus |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
3.1.1.4 | extracellular | - |
Crotalus adamanteus | - |
- |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.1.1.4 | Crotalus adamanteus | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
3.1.1.4 | native enzyme by gel filtration and C18 reverse phase HPLC | Crotalus adamanteus |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
3.1.1.4 | venom | - |
Crotalus adamanteus | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.1.1.4 | 1-hexadecanoyl-2-(1-pyrenedecanoyl)-sn-glycero-3-phosphoglycerol + H2O | micellar substrate | Crotalus adamanteus | ? | - |
? | |
3.1.1.4 | additional information | the enzyme causes endema when applicated to the right footpad of male Swiss mice | Crotalus adamanteus | ? | - |
? |
EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|---|
3.1.1.4 | 37 | - |
assay at | Crotalus adamanteus |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
3.1.1.4 | 8 | - |
assay at | Crotalus adamanteus |
EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|---|
3.1.1.4 | 0.00000872 | - |
1,3-dihydroxy benzene | pH 8.0, 37°C | Crotalus adamanteus | |
3.1.1.4 | 0.00000874 | - |
2,4,6-trihydroxy acetophenone | pH 8.0, 37°C | Crotalus adamanteus | |
3.1.1.4 | 0.00000877 | - |
1,3,5-trihydroxybenzene | pH 8.0, 37°C | Crotalus adamanteus | |
3.1.1.4 | 0.00003 | - |
2,6-dihydroxy acetophenone | pH 8.0, 37°C | Crotalus adamanteus | |
3.1.1.4 | 0.000032 | - |
2,4-dihydroxy acetophenone | pH 8.0, 37°C | Crotalus adamanteus |