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Literature summary extracted from

  • Laguerre, C.; Sanchez-Hernandez, J.C.; Koehler, H.R.; Triebskorn, R.; Capowiez, Y.; Rault, M.; Mazzia, C.
    B-type esterases in the snail Xeropicta derbentina: an enzymological analysis to evaluate their use as biomarkers of pesticide exposure (2009), Environ. Pollut., 157, 199-207.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.1.1 4-nitrophenyl acetate an inhibition of CaE activity by 4-nitrophenyl acetate is observed at substrate concentration higher than 5 mM Xeropicta derbentina
3.1.1.1 chlorpyrifos-oxon CaE activity on 4-nitrophenyl valerate is more sensitive to chlorpyrifos-oxon than CaE activity determined by 4-nitrophenyl acetate and alpha-naphthyl acetate Xeropicta derbentina
3.1.1.1 dichlorvos CaE activities on 4-nitrophenyl acetate and alpha-naphthyl acetate are more sensitive to chlorpyrifos-oxon than CaE activity determined by 4-nitrophenyl valerate Xeropicta derbentina
3.1.1.1 eserine 20% inhibition of CaE activity at 2.5 mM eserine using 4-nitrophenyl valerate as a substrate Xeropicta derbentina
3.1.1.1 additional information not inhibited by carbamates Xeropicta derbentina

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.1.1.1 0.187
-
 4-nitrophenyl valerate at 25°C Xeropicta derbentina
3.1.1.1 0.222
-
 Alpha-naphthyl acetate at 25°C Xeropicta derbentina
3.1.1.1 0.98
-
 4-nitrophenyl acetate at 25°C Xeropicta derbentina

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.1.1.1 cytosol
-
 Xeropicta derbentina 5829
-

Organism

EC Number Organism UniProt Comment Textmining
3.1.1.1 Xeropicta derbentina
-
-
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.1.1.1 192
-
 crude extract, using 4-nitrophenyl acetate as substrate, at 25°C Xeropicta derbentina
3.1.1.1 437
-
 crude extract, using 4-nitrophenyl valerate as substrate, at 25°C Xeropicta derbentina
3.1.1.1 1095
-
 crude extract, using alpha-naphthyl acetate as substrate, at 25°C Xeropicta derbentina

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.1.1 4-nitrophenyl acetate + H2O
-
 Xeropicta derbentina 4-nitrophenol + acetate
-
 ?
3.1.1.1 4-nitrophenyl valerate + H2O
-
 Xeropicta derbentina 4-nitrophenol + valerate
-
 ?
3.1.1.1 alpha-naphthyl acetate + H2O
-
 Xeropicta derbentina 1-naphthol + acetate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.1.1.1 CaE
-
 Xeropicta derbentina

IC50 Value

EC Number IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
3.1.1.1 0.0000224
-
 using 4-nitrophenyl acetate as substrate, at 25°C Xeropicta derbentina dichlorvos
3.1.1.1 0.0000244
-
 using 4-nitrophenyl valerate as substrate, at 25°C Xeropicta derbentina chlorpyrifos-oxon
3.1.1.1 0.0000298
-
 using alpha-naphthyl acetate as substrate, at 25°C Xeropicta derbentina dichlorvos
3.1.1.1 0.002
-
 using 4-nitrophenyl acetate as substrate, at 25°C Xeropicta derbentina chlorpyrifos-oxon
3.1.1.1 0.00321
-
 using alpha-naphthyl acetate as substrate, at 25°C Xeropicta derbentina chlorpyrifos-oxon
3.1.1.1 0.012
-
 using 4-nitrophenyl valerate as substrate, at 25°C Xeropicta derbentina dichlorvos