EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
3.1.2.6 | auxin | enhances activity of both gly I and II | Glycine max | |
3.1.2.6 | additional information | coldnesse enhances gly II transcript expression | Brassica sp. | |
3.1.2.6 | additional information | drought enhances gly II transcript expression | Brassica sp. | |
3.1.2.6 | additional information | salt enhances gly II transcript expression | Brassica sp. | |
3.1.2.6 | additional information | zinc stress enhances gly II transcript expression | Brassica sp. | |
4.4.1.5 | 6-benzylaminopurine | - |
Pisum sativum | |
4.4.1.5 | 6-benzylaminopurine | - |
Nicotiana sp. | |
4.4.1.5 | abscisic acid | - |
Solanum tuberosum | |
4.4.1.5 | auxin | enhances activity of both gly I and II in Glycine max | Glycine max | |
4.4.1.5 | indole acetic acid | stimulation of activity of glyoxalase I | Pisum sativum | |
4.4.1.5 | kinetin | - |
Pisum sativum | |
4.4.1.5 | kinetin | - |
Nicotiana sp. | |
4.4.1.5 | light | red and blue light exposure increases gly I activity in dark-gron Amaranthus sp. indicating expression of enzyme is under stringent regulation by photoreceptors in plants | Amaranthus sp. | |
4.4.1.5 | mannitol | - |
Solanum tuberosum | |
4.4.1.5 | additional information | not only light but a number of other exogenous factors, such as hypoxai, temperature shock, and water stress, transduce their signal through Ca2+ that binds specific target proteins, including kinases, which in turn can activate gly I | Amaranthus sp. | |
4.4.1.5 | additional information | not only light but a number of other exogenous factors, such as hypoxia, temperature shock, and water stress, transduce their signal through Ca2+ that binds specific target proteins, including kinases, which in turn can activate gly I | Triticum aestivum | |
4.4.1.5 | additional information | not only light but a number of other exogenous factors, such as hypoxia, temperature shock, and water stress, transduce their signal through Ca2+ that binds specific target proteins, including kinases, which in turn can activate gly I | Pisum sativum | |
4.4.1.5 | additional information | not only light but a number of other exogenous factors, such as hypoxia, temperature shock, and water stress, transduce their signal through Ca2+ that binds specific target proteins, including kinases, which in turn can activate gly I | Solanum tuberosum | |
4.4.1.5 | additional information | not only light but a number of other exogenous factors, such as hypoxia, temperature shock, and water stress, transduce their signal through Ca2+ that binds specific target proteins, including kinases, which in turn can activate gly I | Glycine max | |
4.4.1.5 | additional information | not only light but a number of other exogenous factors, such as hypoxia, temperature shock, and water stress, transduce their signal through Ca2+ that binds specific target proteins, including kinases, which in turn can activate gly I | Oryza sativa | |
4.4.1.5 | additional information | not only light but a number of other exogenous factors, such as hypoxia, temperature shock, and water stress, transduce their signal through Ca2+ that binds specific target proteins, including kinases, which in turn can activate gly I | Nicotiana sp. | |
4.4.1.5 | additional information | not only light but a number of other exogenous factors, such as hypoxia, temperature shock, and water stress, transduce their signal through Ca2+ that binds specific target proteins, including kinases, which in turn can activate gly I | Brassica sp. | |
4.4.1.5 | additional information | not only light but a number of other exogenous factors, such as hypoxia, temperature shock, and water stress, transduce their signal through Ca2+ that binds specific target proteins, including kinases, which in turn can activate gly I | Aloe vera | |
4.4.1.5 | spermidine | - |
Triticum aestivum | |
4.4.1.5 | spermidine | - |
Pisum sativum | |
4.4.1.5 | spermidine | - |
Solanum tuberosum | |
4.4.1.5 | spermidine | gly I | Amaranthus sp. | |
4.4.1.5 | spermidine | gly I | Oryza sativa | |
4.4.1.5 | spermidine | gly I | Nicotiana sp. | |
4.4.1.5 | spermidine | gly I | Aloe vera |
EC Number | Cloned (Comment) | Organism |
---|---|---|
3.1.2.6 | - |
Arabidopsis thaliana |
3.1.2.6 | Brassica sp. gly II | Brassica sp. |
4.4.1.5 | Brassica sp. gly I, cloning and overexpression in tobacco, transgenic plants tolerate higher concentrations of NaCl | Glycine max |
4.4.1.5 | Brassica sp. gly I, cloning and overexpression in tobacco, transgenic plants tolerate higher concentrations of NaCl | Brassica sp. |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
3.1.2.6 | N,S-bis-carbobenzoxy-glutathione | - |
Arabidopsis thaliana | |
3.1.2.6 | N,S-bis-FMOC-glutathione | - |
Arabidopsis thaliana | |
4.4.1.5 | 1-Naphthaleneacetic acid | activity decreases by approximately 50% during differentiation in Brassica sp. gly I | Brassica sp. | |
4.4.1.5 | 1-Naphthaleneacetic acid | activity decreases by approximately 50% during differentiation in Brassica sp. gly I | Oryza sativa | |
4.4.1.5 | benzyladenine | activity decreases by approximately 50% during differentiation in Brassica sp. gly I | Brassica sp. | |
4.4.1.5 | benzyladenine | activity decreases by approximately 50% during differentiation in Brassica sp. gly I | Oryza sativa | |
4.4.1.5 | Colchicine | decrease of activity of glyoxalase I | Oryza sativa | |
4.4.1.5 | Colchicine | decrease of activity of glyoxalase I | Pisum sativum | |
4.4.1.5 | vinblastine | decrease of activity of glyoxalase I | Oryza sativa | |
4.4.1.5 | vinblastine | decrease of activity of glyoxalase I | Pisum sativum |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
4.4.1.5 | 0.061 | - |
(R)-S-lactoylglutathione | - |
Oryza sativa | |
4.4.1.5 | 0.12 | - |
(R)-S-lactoylglutathione | Brassica sp. gly I | Brassica sp. | |
4.4.1.5 | 1.4 | - |
methylglyoxal | for the hemithioacetal as substrate | Aloe vera |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
3.1.2.6 | cytosol | - |
Zea mays | 5829 | - |
3.1.2.6 | cytosol | - |
Solanum tuberosum | 5829 | - |
3.1.2.6 | cytosol | - |
Glycine max | 5829 | - |
3.1.2.6 | cytosol | - |
Arabidopsis thaliana | 5829 | - |
3.1.2.6 | cytosol | - |
Brassica sp. | 5829 | - |
3.1.2.6 | membrane | associated | Zea mays | 16020 | - |
3.1.2.6 | membrane | associated | Solanum tuberosum | 16020 | - |
3.1.2.6 | membrane | associated | Glycine max | 16020 | - |
3.1.2.6 | membrane | associated | Arabidopsis thaliana | 16020 | - |
3.1.2.6 | membrane | associated | Brassica sp. | 16020 | - |
3.1.2.6 | mitochondrion | - |
Zea mays | 5739 | - |
3.1.2.6 | mitochondrion | - |
Solanum tuberosum | 5739 | - |
3.1.2.6 | mitochondrion | - |
Glycine max | 5739 | - |
3.1.2.6 | mitochondrion | - |
Arabidopsis thaliana | 5739 | - |
3.1.2.6 | mitochondrion | - |
Brassica sp. | 5739 | - |
4.4.1.5 | cytosol | - |
Triticum aestivum | 5829 | - |
4.4.1.5 | cytosol | - |
Pisum sativum | 5829 | - |
4.4.1.5 | cytosol | - |
Amaranthus sp. | 5829 | - |
4.4.1.5 | cytosol | - |
Solanum tuberosum | 5829 | - |
4.4.1.5 | cytosol | - |
Glycine max | 5829 | - |
4.4.1.5 | cytosol | - |
Oryza sativa | 5829 | - |
4.4.1.5 | cytosol | - |
Nicotiana sp. | 5829 | - |
4.4.1.5 | cytosol | - |
Brassica sp. | 5829 | - |
4.4.1.5 | cytosol | - |
Aloe vera | 5829 | - |
4.4.1.5 | membrane | associated | Triticum aestivum | 16020 | - |
4.4.1.5 | membrane | associated | Pisum sativum | 16020 | - |
4.4.1.5 | membrane | associated | Amaranthus sp. | 16020 | - |
4.4.1.5 | membrane | associated | Solanum tuberosum | 16020 | - |
4.4.1.5 | membrane | associated | Glycine max | 16020 | - |
4.4.1.5 | membrane | associated | Oryza sativa | 16020 | - |
4.4.1.5 | membrane | associated | Nicotiana sp. | 16020 | - |
4.4.1.5 | membrane | associated | Brassica sp. | 16020 | - |
4.4.1.5 | membrane | associated | Aloe vera | 16020 | - |
4.4.1.5 | mitochondrion | - |
Triticum aestivum | 5739 | - |
4.4.1.5 | mitochondrion | - |
Pisum sativum | 5739 | - |
4.4.1.5 | mitochondrion | - |
Amaranthus sp. | 5739 | - |
4.4.1.5 | mitochondrion | - |
Solanum tuberosum | 5739 | - |
4.4.1.5 | mitochondrion | - |
Glycine max | 5739 | - |
4.4.1.5 | mitochondrion | - |
Oryza sativa | 5739 | - |
4.4.1.5 | mitochondrion | - |
Nicotiana sp. | 5739 | - |
4.4.1.5 | mitochondrion | - |
Brassica sp. | 5739 | - |
4.4.1.5 | mitochondrion | - |
Aloe vera | 5739 | - |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
3.1.2.6 | Fe3+ | Arabidopsis thaliana mitochondrial and cytosolic gly II can accomodate a number of different metal centers, enzyme contains an iron-zinc binuclear metal center that os essential for activity | Arabidopsis thaliana | |
3.1.2.6 | Mn2+ | no binding to Arabidopsis thaliana mitochondrial enzyme, but binding to cytosolic gly II | Arabidopsis thaliana | |
3.1.2.6 | Zn2+ | binding affinity | Zea mays | |
3.1.2.6 | Zn2+ | binding affinity | Solanum tuberosum | |
3.1.2.6 | Zn2+ | binding affinity | Glycine max | |
3.1.2.6 | Zn2+ | binding affinity | Arabidopsis thaliana | |
3.1.2.6 | Zn2+ | binding affinity | Brassica sp. | |
4.4.1.5 | Ca2+ | activation of gly I | Triticum aestivum | |
4.4.1.5 | Ca2+ | activation of gly I | Pisum sativum | |
4.4.1.5 | Ca2+ | activation of gly I | Amaranthus sp. | |
4.4.1.5 | Ca2+ | activation of gly I | Solanum tuberosum | |
4.4.1.5 | Ca2+ | activation of gly I | Glycine max | |
4.4.1.5 | Ca2+ | activation of gly I | Oryza sativa | |
4.4.1.5 | Ca2+ | activation of gly I | Nicotiana sp. | |
4.4.1.5 | Ca2+ | activation of gly I | Brassica sp. | |
4.4.1.5 | Ca2+ | activation of gly I | Aloe vera | |
4.4.1.5 | Zn2+ | activates | Brassica juncea | |
4.4.1.5 | Zn2+ | binding affinity | Triticum aestivum | |
4.4.1.5 | Zn2+ | binding affinity | Pisum sativum | |
4.4.1.5 | Zn2+ | binding affinity | Amaranthus sp. | |
4.4.1.5 | Zn2+ | binding affinity | Solanum tuberosum | |
4.4.1.5 | Zn2+ | binding affinity | Glycine max | |
4.4.1.5 | Zn2+ | binding affinity | Oryza sativa | |
4.4.1.5 | Zn2+ | binding affinity | Nicotiana sp. | |
4.4.1.5 | Zn2+ | binding affinity | Brassica sp. | |
4.4.1.5 | Zn2+ | binding affinity | Aloe vera |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
3.1.2.6 | 26000 | - |
Zea mays gly II enzyme is a monomer | Zea mays |
4.4.1.5 | 37000 | - |
- |
Triticum aestivum |
4.4.1.5 | 37000 | - |
Triticum aestivum gly I enzyme is a monomer | Triticum aestivum |
4.4.1.5 | 44000 | - |
- |
Aloe vera |
4.4.1.5 | 44000 | - |
enzyme is a monomer | Aloe vera |
4.4.1.5 | 58000 | - |
- |
Brassica oleracea |
4.4.1.5 | 58000 | - |
Brassica gly I enzyme | Brassica sp. |
4.4.1.5 | 60000 | - |
enzyme has two subunits | Glycine max |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.1.2.6 | additional information | Zea mays | the glyoxalase system is an ubiquitous pathway for the detoxification of highly reactive ketoaldehydes | ? | - |
? | |
3.1.2.6 | additional information | Solanum tuberosum | the glyoxalase system is an ubiquitous pathway for the detoxification of highly reactive ketoaldehydes | ? | - |
? | |
3.1.2.6 | additional information | Glycine max | the glyoxalase system is an ubiquitous pathway for the detoxification of highly reactive ketoaldehydes | ? | - |
? | |
3.1.2.6 | additional information | Arabidopsis thaliana | the glyoxalase system is an ubiquitous pathway for the detoxification of highly reactive ketoaldehydes | ? | - |
? | |
3.1.2.6 | additional information | Brassica sp. | the glyoxalase system is an ubiquitous pathway for the detoxification of highly reactive ketoaldehydes | ? | - |
? | |
3.1.2.6 | S-D-lactoylglutathione + H2O | Zea mays | second step in the glyoxalase system | D-lactate + glutathione | - |
? | |
3.1.2.6 | S-D-lactoylglutathione + H2O | Solanum tuberosum | second step in the glyoxalase system | D-lactate + glutathione | - |
? | |
3.1.2.6 | S-D-lactoylglutathione + H2O | Glycine max | second step in the glyoxalase system | D-lactate + glutathione | - |
? | |
3.1.2.6 | S-D-lactoylglutathione + H2O | Arabidopsis thaliana | second step in the glyoxalase system | D-lactate + glutathione | - |
? | |
3.1.2.6 | S-D-lactoylglutathione + H2O | Brassica sp. | second step in the glyoxalase system | D-lactate + glutathione | - |
? | |
4.4.1.5 | methylglyoxal + glutathione | Triticum aestivum | first step in the glyoxalase system | (R)-S-lactoylglutathione | - |
r | |
4.4.1.5 | methylglyoxal + glutathione | Pisum sativum | first step in the glyoxalase system | (R)-S-lactoylglutathione | - |
r | |
4.4.1.5 | methylglyoxal + glutathione | Solanum tuberosum | first step in the glyoxalase system | (R)-S-lactoylglutathione | - |
r | |
4.4.1.5 | methylglyoxal + glutathione | Glycine max | first step in the glyoxalase system | (R)-S-lactoylglutathione | - |
r | |
4.4.1.5 | methylglyoxal + glutathione | Oryza sativa | first step in the glyoxalase system | (R)-S-lactoylglutathione | - |
r | |
4.4.1.5 | methylglyoxal + glutathione | Nicotiana sp. | first step in the glyoxalase system | (R)-S-lactoylglutathione | - |
r | |
4.4.1.5 | methylglyoxal + glutathione | Brassica sp. | first step in the glyoxalase system | (R)-S-lactoylglutathione | - |
r | |
4.4.1.5 | methylglyoxal + glutathione | Aloe vera | first step in the glyoxalase system | (R)-S-lactoylglutathione | - |
r | |
4.4.1.5 | methylglyoxal + glutathione | Amaranthus sp. | first step in the glyoxalase system | (R)S-lactoylglutathione | - |
r | |
4.4.1.5 | additional information | Triticum aestivum | the glyoxalase system is an ubiquitous pathway for the detoxification of highly reactive ketoaldehydes | ? | - |
? | |
4.4.1.5 | additional information | Pisum sativum | the glyoxalase system is an ubiquitous pathway for the detoxification of highly reactive ketoaldehydes | ? | - |
? | |
4.4.1.5 | additional information | Amaranthus sp. | the glyoxalase system is an ubiquitous pathway for the detoxification of highly reactive ketoaldehydes | ? | - |
? | |
4.4.1.5 | additional information | Solanum tuberosum | the glyoxalase system is an ubiquitous pathway for the detoxification of highly reactive ketoaldehydes | ? | - |
? | |
4.4.1.5 | additional information | Glycine max | the glyoxalase system is an ubiquitous pathway for the detoxification of highly reactive ketoaldehydes | ? | - |
? | |
4.4.1.5 | additional information | Oryza sativa | the glyoxalase system is an ubiquitous pathway for the detoxification of highly reactive ketoaldehydes | ? | - |
? | |
4.4.1.5 | additional information | Nicotiana sp. | the glyoxalase system is an ubiquitous pathway for the detoxification of highly reactive ketoaldehydes | ? | - |
? | |
4.4.1.5 | additional information | Brassica sp. | the glyoxalase system is an ubiquitous pathway for the detoxification of highly reactive ketoaldehydes | ? | - |
? | |
4.4.1.5 | additional information | Aloe vera | the glyoxalase system is an ubiquitous pathway for the detoxification of highly reactive ketoaldehydes | ? | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.1.2.6 | Arabidopsis thaliana | - |
- |
- |
3.1.2.6 | Brassica sp. | - |
- |
- |
3.1.2.6 | Glycine max | - |
soybean | - |
3.1.2.6 | Solanum tuberosum | - |
- |
- |
3.1.2.6 | Zea mays | - |
- |
- |
4.4.1.5 | Aloe vera | - |
- |
- |
4.4.1.5 | Amaranthus sp. | - |
- |
- |
4.4.1.5 | Brassica juncea | - |
- |
- |
4.4.1.5 | Brassica oleracea | - |
- |
- |
4.4.1.5 | Brassica sp. | - |
- |
- |
4.4.1.5 | Glycine max | - |
soybean | - |
4.4.1.5 | Nicotiana sp. | - |
- |
- |
4.4.1.5 | Oryza sativa | - |
- |
- |
4.4.1.5 | Pisum sativum | - |
- |
- |
4.4.1.5 | Solanum lycopersicum | - |
- |
- |
4.4.1.5 | Solanum tuberosum | - |
- |
- |
4.4.1.5 | Triticum aestivum | - |
- |
- |
4.4.1.5 | Triticum aestivum | - |
wheat | - |
EC Number | Purification (Comment) | Organism |
---|---|---|
3.1.2.6 | - |
Zea mays |
3.1.2.6 | Arabidopsis thaliana gly II | Arabidopsis thaliana |
3.1.2.6 | Brassica sp. gly II | Brassica sp. |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
3.1.2.6 | flower bud | differential expression of mitochondrial and cytosolic gly II | Arabidopsis thaliana | - |
3.1.2.6 | flower bud | differential expression of mitochondrial and cytosolic gly II | Brassica sp. | - |
3.1.2.6 | leaf | gly II | Zea mays | - |
3.1.2.6 | leaf | gly II | Arabidopsis thaliana | - |
3.1.2.6 | leaf | gly II | Brassica sp. | - |
3.1.2.6 | root | differential expression of mitochondrial and cytosolic gly II | Zea mays | - |
3.1.2.6 | root | differential expression of mitochondrial and cytosolic gly II | Arabidopsis thaliana | - |
3.1.2.6 | root | differential expression of mitochondrial and cytosolic gly II | Brassica sp. | - |
4.4.1.5 | additional information | gly I is present in all types of cells and tissues | Triticum aestivum | - |
4.4.1.5 | additional information | gly I is present in all types of cells and tissues | Pisum sativum | - |
4.4.1.5 | additional information | gly I is present in all types of cells and tissues | Amaranthus sp. | - |
4.4.1.5 | additional information | gly I is present in all types of cells and tissues | Solanum tuberosum | - |
4.4.1.5 | additional information | gly I is present in all types of cells and tissues | Glycine max | - |
4.4.1.5 | additional information | gly I is present in all types of cells and tissues | Oryza sativa | - |
4.4.1.5 | additional information | gly I is present in all types of cells and tissues | Nicotiana sp. | - |
4.4.1.5 | additional information | gly I is present in all types of cells and tissues | Brassica sp. | - |
4.4.1.5 | additional information | gly I is present in all types of cells and tissues | Aloe vera | - |
4.4.1.5 | additional information | present in all types of cells and tissues | Solanum lycopersicum | - |
4.4.1.5 | phloem | - |
Triticum aestivum | - |
4.4.1.5 | phloem | - |
Pisum sativum | - |
4.4.1.5 | phloem | - |
Amaranthus sp. | - |
4.4.1.5 | phloem | - |
Solanum tuberosum | - |
4.4.1.5 | phloem | - |
Glycine max | - |
4.4.1.5 | phloem | - |
Oryza sativa | - |
4.4.1.5 | phloem | - |
Nicotiana sp. | - |
4.4.1.5 | phloem | - |
Brassica sp. | - |
4.4.1.5 | phloem | - |
Aloe vera | - |
4.4.1.5 | phloem | preferentially accumulated in phloem and sieve cells | Solanum lycopersicum | - |
4.4.1.5 | sieve cell | - |
Triticum aestivum | - |
4.4.1.5 | sieve cell | - |
Pisum sativum | - |
4.4.1.5 | sieve cell | - |
Amaranthus sp. | - |
4.4.1.5 | sieve cell | - |
Solanum tuberosum | - |
4.4.1.5 | sieve cell | - |
Glycine max | - |
4.4.1.5 | sieve cell | - |
Oryza sativa | - |
4.4.1.5 | sieve cell | - |
Nicotiana sp. | - |
4.4.1.5 | sieve cell | - |
Brassica sp. | - |
4.4.1.5 | sieve cell | - |
Aloe vera | - |
4.4.1.5 | sieve cell | preferentially accumulated in phloem and sieve cells | Solanum lycopersicum | - |
4.4.1.5 | tuber | found to be conserved in tubers among different potato variants | Solanum tuberosum | - |
EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
4.4.1.5 | additional information | - |
activity of glyoxalase I in Pisum sativum shows linear progression with development of shoots and roots of seedlings, cell division and proliferation further modulate the activity | Pisum sativum |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.1.2.6 | additional information | the glyoxalase system is an ubiquitous pathway for the detoxification of highly reactive ketoaldehydes | Zea mays | ? | - |
? | |
3.1.2.6 | additional information | the glyoxalase system is an ubiquitous pathway for the detoxification of highly reactive ketoaldehydes | Solanum tuberosum | ? | - |
? | |
3.1.2.6 | additional information | the glyoxalase system is an ubiquitous pathway for the detoxification of highly reactive ketoaldehydes | Glycine max | ? | - |
? | |
3.1.2.6 | additional information | the glyoxalase system is an ubiquitous pathway for the detoxification of highly reactive ketoaldehydes | Arabidopsis thaliana | ? | - |
? | |
3.1.2.6 | additional information | the glyoxalase system is an ubiquitous pathway for the detoxification of highly reactive ketoaldehydes | Brassica sp. | ? | - |
? | |
3.1.2.6 | S-D-lactoylglutathione + H2O | second step in the glyoxalase system | Zea mays | D-lactate + glutathione | - |
? | |
3.1.2.6 | S-D-lactoylglutathione + H2O | second step in the glyoxalase system | Solanum tuberosum | D-lactate + glutathione | - |
? | |
3.1.2.6 | S-D-lactoylglutathione + H2O | second step in the glyoxalase system | Glycine max | D-lactate + glutathione | - |
? | |
3.1.2.6 | S-D-lactoylglutathione + H2O | second step in the glyoxalase system | Arabidopsis thaliana | D-lactate + glutathione | - |
? | |
3.1.2.6 | S-D-lactoylglutathione + H2O | second step in the glyoxalase system | Brassica sp. | D-lactate + glutathione | - |
? | |
4.4.1.5 | glutathione + methylglyoxal | - |
Aloe vera | S-D-lactoylglutathione | - |
? | |
4.4.1.5 | methylglyoxal + glutathione | first step in the glyoxalase system | Triticum aestivum | (R)-S-lactoylglutathione | - |
r | |
4.4.1.5 | methylglyoxal + glutathione | first step in the glyoxalase system | Pisum sativum | (R)-S-lactoylglutathione | - |
r | |
4.4.1.5 | methylglyoxal + glutathione | first step in the glyoxalase system | Solanum tuberosum | (R)-S-lactoylglutathione | - |
r | |
4.4.1.5 | methylglyoxal + glutathione | first step in the glyoxalase system | Glycine max | (R)-S-lactoylglutathione | - |
r | |
4.4.1.5 | methylglyoxal + glutathione | first step in the glyoxalase system | Oryza sativa | (R)-S-lactoylglutathione | - |
r | |
4.4.1.5 | methylglyoxal + glutathione | first step in the glyoxalase system | Nicotiana sp. | (R)-S-lactoylglutathione | - |
r | |
4.4.1.5 | methylglyoxal + glutathione | first step in the glyoxalase system | Brassica sp. | (R)-S-lactoylglutathione | - |
r | |
4.4.1.5 | methylglyoxal + glutathione | first step in the glyoxalase system | Aloe vera | (R)-S-lactoylglutathione | - |
r | |
4.4.1.5 | methylglyoxal + glutathione | first step in the glyoxalase system | Amaranthus sp. | (R)S-lactoylglutathione | - |
r | |
4.4.1.5 | methylglyoxal + glutathione | non-enzymatic formation of hemithioacteal as substrate for gly I | Aloe vera | S-((R)-lactoyl)glutathione | - |
? | |
4.4.1.5 | methylglyoxal + glutathione | non-enzymatic formation of hemithioacteal as substrate for gly I. The active site of gly I has binding affinity for zinc ion and hemithioacetal, and his His residue might be important for its catalytic activity | Brassica juncea | S-((R)-lactoyl)glutathione | - |
? | |
4.4.1.5 | additional information | the glyoxalase system is an ubiquitous pathway for the detoxification of highly reactive ketoaldehydes | Triticum aestivum | ? | - |
? | |
4.4.1.5 | additional information | the glyoxalase system is an ubiquitous pathway for the detoxification of highly reactive ketoaldehydes | Pisum sativum | ? | - |
? | |
4.4.1.5 | additional information | the glyoxalase system is an ubiquitous pathway for the detoxification of highly reactive ketoaldehydes | Amaranthus sp. | ? | - |
? | |
4.4.1.5 | additional information | the glyoxalase system is an ubiquitous pathway for the detoxification of highly reactive ketoaldehydes | Solanum tuberosum | ? | - |
? | |
4.4.1.5 | additional information | the glyoxalase system is an ubiquitous pathway for the detoxification of highly reactive ketoaldehydes | Glycine max | ? | - |
? | |
4.4.1.5 | additional information | the glyoxalase system is an ubiquitous pathway for the detoxification of highly reactive ketoaldehydes | Oryza sativa | ? | - |
? | |
4.4.1.5 | additional information | the glyoxalase system is an ubiquitous pathway for the detoxification of highly reactive ketoaldehydes | Nicotiana sp. | ? | - |
? | |
4.4.1.5 | additional information | the glyoxalase system is an ubiquitous pathway for the detoxification of highly reactive ketoaldehydes | Brassica sp. | ? | - |
? | |
4.4.1.5 | additional information | the glyoxalase system is an ubiquitous pathway for the detoxification of highly reactive ketoaldehydes | Aloe vera | ? | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
3.1.2.6 | monomer | - |
Zea mays |
4.4.1.5 | dimer | 2 * 27000-29000 | Brassica oleracea |
4.4.1.5 | heterodimer | enzyme has 2 subunits | Brassica sp. |
4.4.1.5 | heterodimer | Glycine max gly I enzyme has 2 subunits | Glycine max |
4.4.1.5 | monomer | 1 * 37000 | Triticum aestivum |
4.4.1.5 | monomer | 1 * 44000 | Aloe vera |
4.4.1.5 | monomer | Aloe vera gly I | Aloe vera |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
3.1.2.6 | glyoxalase II | - |
Zea mays |
3.1.2.6 | glyoxalase II | - |
Solanum tuberosum |
3.1.2.6 | glyoxalase II | - |
Glycine max |
3.1.2.6 | glyoxalase II | - |
Arabidopsis thaliana |
3.1.2.6 | glyoxalase II | - |
Brassica sp. |
3.1.2.6 | hydroxyacylglutathione hydrolase | - |
Zea mays |
3.1.2.6 | hydroxyacylglutathione hydrolase | - |
Solanum tuberosum |
3.1.2.6 | hydroxyacylglutathione hydrolase | - |
Glycine max |
3.1.2.6 | hydroxyacylglutathione hydrolase | - |
Arabidopsis thaliana |
3.1.2.6 | hydroxyacylglutathione hydrolase | - |
Brassica sp. |
4.4.1.5 | glyoxalase I | - |
Triticum aestivum |
4.4.1.5 | glyoxalase I | - |
Pisum sativum |
4.4.1.5 | glyoxalase I | - |
Amaranthus sp. |
4.4.1.5 | glyoxalase I | - |
Solanum tuberosum |
4.4.1.5 | glyoxalase I | - |
Glycine max |
4.4.1.5 | glyoxalase I | - |
Oryza sativa |
4.4.1.5 | glyoxalase I | - |
Nicotiana sp. |
4.4.1.5 | glyoxalase I | - |
Brassica sp. |
4.4.1.5 | glyoxalase I | - |
Aloe vera |
4.4.1.5 | lactoylglutathione methylglyoxal lyase | - |
Triticum aestivum |
4.4.1.5 | lactoylglutathione methylglyoxal lyase | - |
Pisum sativum |
4.4.1.5 | lactoylglutathione methylglyoxal lyase | - |
Amaranthus sp. |
4.4.1.5 | lactoylglutathione methylglyoxal lyase | - |
Solanum tuberosum |
4.4.1.5 | lactoylglutathione methylglyoxal lyase | - |
Glycine max |
4.4.1.5 | lactoylglutathione methylglyoxal lyase | - |
Oryza sativa |
4.4.1.5 | lactoylglutathione methylglyoxal lyase | - |
Nicotiana sp. |
4.4.1.5 | lactoylglutathione methylglyoxal lyase | - |
Brassica sp. |
4.4.1.5 | lactoylglutathione methylglyoxal lyase | - |
Aloe vera |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
4.4.1.5 | glutathione | - |
Triticum aestivum | |
4.4.1.5 | glutathione | - |
Pisum sativum | |
4.4.1.5 | glutathione | - |
Amaranthus sp. | |
4.4.1.5 | glutathione | - |
Solanum tuberosum | |
4.4.1.5 | glutathione | - |
Glycine max | |
4.4.1.5 | glutathione | - |
Oryza sativa | |
4.4.1.5 | glutathione | - |
Nicotiana sp. | |
4.4.1.5 | glutathione | - |
Brassica sp. | |
4.4.1.5 | glutathione | - |
Aloe vera |
EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|---|
3.1.2.6 | 0.89 | - |
N,S-bis-FMOC-glutathione | - |
Arabidopsis thaliana | |
3.1.2.6 | 2.3 | - |
di-carbobenzoxyglutathione | - |
Arabidopsis thaliana |
EC Number | Organism | Comment | pI Value Maximum | pI Value |
---|---|---|---|---|
3.1.2.6 | Zea mays | acidic pI of plant gly II ranges from 4.5-6.2 | - |
additional information |
3.1.2.6 | Solanum tuberosum | acidic pI of plant gly II ranges from 4.5-6.2 | - |
additional information |
3.1.2.6 | Glycine max | acidic pI of plant gly II ranges from 4.5-6.2 | - |
additional information |
3.1.2.6 | Arabidopsis thaliana | acidic pI of plant gly II ranges from 4.5-6.2 | - |
additional information |
3.1.2.6 | Brassica sp. | acidic pI of plant gly II ranges from 4.5-6.2 | - |
additional information |
4.4.1.5 | Triticum aestivum | plant gly I ranges from 4.7-5.1 | - |
additional information |
4.4.1.5 | Pisum sativum | plant gly I ranges from 4.7-5.1 | - |
additional information |
4.4.1.5 | Amaranthus sp. | plant gly I ranges from 4.7-5.1 | - |
additional information |
4.4.1.5 | Solanum tuberosum | plant gly I ranges from 4.7-5.1 | - |
additional information |
4.4.1.5 | Glycine max | plant gly I ranges from 4.7-5.1 | - |
additional information |
4.4.1.5 | Nicotiana sp. | plant gly I ranges from 4.7-5.1 | - |
additional information |
4.4.1.5 | Brassica sp. | plant gly I ranges from 4.7-5.1 | - |
additional information |
4.4.1.5 | Aloe vera | - |
- |
7.8 |
4.4.1.5 | Oryza sativa | mitochondrial form of Oryza sativa gly I | - |
8.1 |