EC Number | Protein Variants | Comment | Organism |
---|---|---|---|
2.4.1.221 | additional information | analysis of O-fut 1 homozygous mutant cells shows that O-fut1 is required for the endocytic transportation of Notch to the early endosome which is shown to be independent of the O-fucosyltransferase activity of O-fut1 | Drosophila melanogaster |
2.4.1.221 | additional information | O-fut 1 overexpression and analysis of O-fut 1 homozygous mutant cells indicates that O-fut 1 promotes the turnover of Notch, which consequently downregulates Notch signaling | Drosophila melanogaster |
2.4.1.221 | additional information | O-fut1 protein added to conditioned medium and endocytosed is sufficient to rescue normal Notch transportation to the early endosome in O-fut1 knockdown cells | Drosophila melanogaster |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.4.1.221 | Drosophila melanogaster | - |
- |
- |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.4.1.221 | O-fucosyltransferase O-fut 1 | - |
Drosophila melanogaster |
2.4.1.221 | OFUT1 | - |
Drosophila melanogaster |