Literature summary extracted from
Doerr, A.J.; Pacini, N.; Abete, M.C.; Prearo, M.; Elia, A.C.
Effects of a selenium-enriched diet on antioxidant response in adult crayfish (Procambarus clarkii) (2008), Chemosphere, 73, 1090-1095.
Activating Compound
EC Number |
Activating Compound |
Comment |
Organism |
Structure |
---|
4.4.1.5 |
additional information |
1.21 mg/kg crayfish, selenium-enriched diet, female crayfish, results in a tendency to an increased enzyme activity |
Procambarus clarkii |
|
Inhibitors
EC Number |
Inhibitors |
Comment |
Organism |
Structure |
---|
4.4.1.5 |
additional information |
1.21 mg/kg crayfish, selenium-enriched diet, male crayfish, shows a lowered enzyme activity, 85% inhibited at day 30, 45% inhibited at day 50. A depletion of enzyme activity indicates a compromised detixificant ability against peroxidative metabolites. Since selenium affects only treated males, it seems that males are more susceptible than females |
Procambarus clarkii |
|
Natural Substrates/ Products (Substrates)
EC Number |
Natural Substrates |
Organism |
Comment (Nat. Sub.) |
Natural Products |
Comment (Nat. Pro.) |
Rev. |
Reac. |
---|
4.4.1.5 |
additional information |
Procambarus clarkii |
glyoxalase I activity is involved in the detoxification of toxic metabolites produced during lipid peroxidation |
? |
- |
? |
|
Organism
EC Number |
Organism |
UniProt |
Comment |
Textmining |
---|
4.4.1.5 |
Procambarus clarkii |
- |
crayfish, adult, female and male |
- |
Substrates and Products (Substrate)
EC Number |
Substrates |
Comment Substrates |
Organism |
Products |
Comment (Products) |
Rev. |
Reac. |
---|
4.4.1.5 |
methylglyoxal + glutathione |
the hemiacetal of methylglyoxal + glutathione is used as substrate, 25°C |
Procambarus clarkii |
S-((R)-lactoyl)glutathione |
the formation is measured by monitoring the increase of absorbance at 240 nm |
? |
|
4.4.1.5 |
additional information |
glyoxalase I activity is involved in the detoxification of toxic metabolites produced during lipid peroxidation |
Procambarus clarkii |
? |
- |
? |
|
Temperature Optimum [°C]
EC Number |
Temperature Optimum [°C] |
Temperature Optimum Maximum [°C] |
Comment |
Organism |
---|
4.4.1.5 |
25 |
- |
assay at |
Procambarus clarkii |