Literature summary extracted from

Gulcan, H.O.; Liu, Y.; Duffel, M.W.
Pentachlorophenol and other chlorinated phenols are substrates for human hydroxysteroid sulfotransferase hSULT2A1 (2008), Chem. Res. Toxicol., 21, 1503-1508.

Cloned(Commentary)

EC Number	Cloned (Comment)	Organism
2.8.2.2	SULT2A1, expression in Escherichia coli	Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
2.8.2.2	3'-phosphoadenylyl sulfate + dehydroepiandrosterone	Homo sapiens	-	adenosine 3',5'-bisphosphate + dehydroepiandrosterone 3-sulfate	-	?

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.8.2.2	Homo sapiens	-	-	-

Purification (Commentary)

EC Number	Purification (Comment)	Organism
2.8.2.2	recombinant SULT2A1 from Escherichia coli by anion exchange chromatography, ultrafiltration, and hydroxyapatite chromatography	Homo sapiens

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2.8.2.2	3'-phosphoadenylyl sulfate + dehydroepiandrosterone	-	Homo sapiens	adenosine 3',5'-bisphosphate + dehydroepiandrosterone 3-sulfate	-	?
2.8.2.2	additional information	pentachlorophenols, tetrachlorophenols, and trichlorophenols are substrates of isozyme SULT2A1, while mono- and dichlorophenol are poor substrates, cf. EC 2.8.2.15	Homo sapiens	?	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
2.8.2.2	hydroxysteroid sulfotransferase	-	Homo sapiens
2.8.2.2	More	cf. EC 2.8.2.15	Homo sapiens
2.8.2.2	SULT2A1	-	Homo sapiens

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)