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Literature summary extracted from

  • Chen, B.H.; Baganz, F.; Woodley, J.M.
    Modelling and optimization of a transketolase-mediated carbon-carbon bond formation reaction (2007), Chem. Eng. Sci., 62, 3178-3184.
No PubMed abstract available

Application

EC Number Application Comment Organism
2.2.1.1 additional information development of a comprehensive reaction model for a transketolase mediated carbon-carbon formation, based on the synthesis of erythrulose, which includes component degradation as a function of time and concentration as well as glycolaldehyde toxicity towards the enzyme and which can perform detailed simulations and link bioconversion to upstream fermentation and downstream product purification to determine optimal operating strategies to minimise process costs synthetic construct

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.2.1.1 glycolaldehyde
-
 synthetic construct

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.2.1.1 Mg2+
-
 synthetic construct

Organism

EC Number Organism UniProt Comment Textmining
2.2.1.1 synthetic construct
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.2.1.1 beta-hydroxypyruvate + glycolaldehyde
-
 synthetic construct L-erythrulose + CO2
-
 ?

pH Range

EC Number pH Minimum pH Maximum Comment Organism
2.2.1.1 7 9
-
 synthetic construct

Cofactor

EC Number Cofactor Comment Organism Structure
2.2.1.1 thiamine diphosphate
-
 synthetic construct