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Literature summary extracted from

  • Anglister, L.; Etlin, A.; Finkel, E.; Durrant, A.R.; Lev-Tov, A.
    Cholinesterases in development and disease (2008), Chem. Biol. Interact., 175, 92-100.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.1.8 iso-ompa specific for BuChE Mus musculus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.1.1.8 extracellular serum Mus musculus
-
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.1.8 additional information Mus musculus butyrylcholinesterase to acetylcholinesterase ratio in mouse sera decreases from 6:1 in wild-type control to 3:1 in mdx-mice ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.1.1.8 Mus musculus
-
 wild-type mice and mdx-mice with adult mdx-muscles malformed with distorted neuromuscular junctions and impaired regulation of acetylcholine receptors
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.1.8 additional information butyrylcholinesterase is abundant in the central and peripheral nervous system and also in other tissues Mus musculus
-
3.1.1.8 nervous system central and perpheral Mus musculus
-
3.1.1.8 serum BuChE activity is markedly lower in serum of mdx-mice than in wild-type mouse serum, overview Mus musculus
-
3.1.1.8 skeletal muscle
-
 Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.1.8 butyrylthiocholine + H2O detection using 5,5'-dithiobis(2-nitrobenzoic acid) Mus musculus butyrate + thiocholine
-
 ?
3.1.1.8 additional information butyrylcholinesterase to acetylcholinesterase ratio in mouse sera decreases from 6:1 in wild-type control to 3:1 in mdx-mice Mus musculus ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.1.1.8 BuChE
-
 Mus musculus
3.1.1.8 butyrylcholinesterase
-
 Mus musculus