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Literature summary extracted from

  • Lynex, C.N.; Li, Z.; Chen, M.L.; Toh, K.Y.; Low, R.W.; Goh, D.L.; Tay, S.K.
    Identification and molecular characterization of a novel PDE4D11 cAMP-specific phosphodiesterase isoform (2008), Cell. Signal., 20, 2247-2255.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.1.4.53 expressed in Neuro-2A and NIH-3T3 cells Mus musculus

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.4.53 IBMX non-selective PDE inhibitor Mus musculus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.1.4.53 cytosol
-
 Mus musculus 5829
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.1.4.53 79030
-
 calculated from amino acid sequence Mus musculus

Organism

EC Number Organism UniProt Comment Textmining
3.1.4.53 Mus musculus B1PSD9
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.4.53 brain in the brain, PDE4D11 expression levels increase in the cerebellum, but decrease in the hippocampus with progressive age Mus musculus
-
3.1.4.53 brain stem
-
 Mus musculus
-
3.1.4.53 cerebellum PDE4D11 expression levels increase in the cerebellum with progressive age Mus musculus
-
3.1.4.53 cerebrum
-
 Mus musculus
-
3.1.4.53 heart lowest expression in heart Mus musculus
-
3.1.4.53 hippocampus PDE4D11 expression levels decrease in the hippocampus with progressive age Mus musculus
-
3.1.4.53 kidney
-
 Mus musculus
-
3.1.4.53 liver highest expression level Mus musculus
-
3.1.4.53 lung
-
 Mus musculus
-
3.1.4.53 olfactory bulb
-
 Mus musculus
-
3.1.4.53 spleen highest expression level Mus musculus
-
3.1.4.53 testis
-
 Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.4.53 3',5'-cAMP + H2O
-
 Mus musculus 5'-AMP
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.1.4.53 cAMP-specific phosphodiesterase 4D11
-
 Mus musculus
3.1.4.53 PDE4D11 isoform Mus musculus