Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Rajan, L.A.; Joseph, T.C.; Thampuran, N.; James, R.; Kumar, K.A.; Viswanathan, C.; Bansal, K.C.
    Cloning and heterologous expression of ectoine biosynthesis genes from Bacillus halodurans in Escherichia coli (2008), Biotechnol. Lett., 30, 1403-1407.
    View publication on PubMed

Application

EC Number Application Comment Organism
4.2.1.108 biotechnology ectoine has importance in dermopharmacy as anti ageing agents in skin creams, as components of shampoo, for oral care and as adjuvants for vaccines Halalkalibacterium halodurans

Cloned(Commentary)

EC Number Cloned (Comment) Organism
4.2.1.108 the ectABC gene cluster is expressed in Escherichia coli M15 (pREP4) by vector pQE30 Halalkalibacterium halodurans

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
4.2.1.108 15000
-
 SDS-PAGE, calculated Halalkalibacterium halodurans

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.2.1.108 N4-acetyl-L-2,4-diaminobutyrate Halalkalibacterium halodurans
-
 2-methyl-1,4,5,6-tetrahydropyrimidine-4-carboxylic acid + H2O
-
 ?
4.2.1.108 N4-acetyl-L-2,4-diaminobutyrate Halalkalibacterium halodurans
-
 L-ectoine + H2O
-
 ?
4.2.1.108 N4-acetyl-L-2,4-diaminobutyrate Halalkalibacterium halodurans TCJAR021
-
 2-methyl-1,4,5,6-tetrahydropyrimidine-4-carboxylic acid + H2O
-
 ?
4.2.1.108 N4-acetyl-L-2,4-diaminobutyrate Halalkalibacterium halodurans TCJAR021
-
 L-ectoine + H2O
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
4.2.1.108 Halalkalibacterium halodurans A5A5G3 the ectABC gene cluster expressed in Escherichia coli M15 (pREP4)
-
4.2.1.108 Halalkalibacterium halodurans TCJAR021 A5A5G3 the ectABC gene cluster expressed in Escherichia coli M15 (pREP4)
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.2.1.108 N4-acetyl-L-2,4-diaminobutyrate
-
 Halalkalibacterium halodurans 2-methyl-1,4,5,6-tetrahydropyrimidine-4-carboxylic acid + H2O
-
 ?
4.2.1.108 N4-acetyl-L-2,4-diaminobutyrate
-
 Halalkalibacterium halodurans TCJAR021 2-methyl-1,4,5,6-tetrahydropyrimidine-4-carboxylic acid + H2O
-
 ?
4.2.1.108 N4-acetyl-L-2,4-diaminobutyrate
-
 Halalkalibacterium halodurans L-ectoine + H2O
-
 ?
4.2.1.108 N4-acetyl-L-2,4-diaminobutyrate
-
 Halalkalibacterium halodurans TCJAR021 L-ectoine + H2O
-
 ?

Synonyms

EC Number Synonyms Comment Organism
4.2.1.108 ectoine synthase
-
 Halalkalibacterium halodurans

pI Value

EC Number Organism Comment pI Value Maximum pI Value
4.2.1.108 Halalkalibacterium halodurans calculated
-
 4.93