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Literature summary extracted from

  • Lee, S.H.; Park, J.S.; Kim, S.K.; Ahn, C.B.; Je, J.Y.
    Chitooligosaccharides suppress the level of protein expression and acetylcholinesterase activity induced by Abeta25-35 in PC12 cells (2009), Bioorg. Med. Chem. Lett., 19, 860-862.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.1.1.7 additional information beta-amyloid peptides Abeta25-35 induce AChE protein expression in PC12 cell lines Rattus norvegicus

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.1.7 chitooligosaccharides 90-COSs and 50-COSs are prepared from 90% and 50% deacetylated chitosan, cellular AChE activity is decreased with increasing concentration of 90-MMWCOS chitooligosaccharides in PC12 cell lines, the 90-COSs exhibit more potent AChE inhibitory activities compared to 50-COSs, while 90-MMWCOS, 1-5 kDa, in the 90COSs show the highest activity, overview Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
3.1.1.7 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.1.7 PC-12 cell
-
 Rattus norvegicus
-

Synonyms

EC Number Synonyms Comment Organism
3.1.1.7 AChE
-
 Rattus norvegicus